SCHEMBL13324847

SCHEMBL13324847

COc1c(C)cc(Cc2cc(C)c(OC(=O)c3ccc(C(=O)Oc4ccc(Cc5ccc(OC(=O)c6ccc(C(C)=O)cc6)cc5)cc4)cc3)c(C)c2)cc1C

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 11/20 0.46
▸ MAPT P10636 7/20 0.44
▸ GLA P06280 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ LMNA P02545 2/20 0.42
▸ GAA P10253 1/20 0.42
▸ MAOB P27338 1/20 0.40
▸ MEN1 O00255 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CYP2C9 P11712 1/20 0.39
▸ CYP2C19 P33261 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ GFER P55789 1/20 0.38
▸ PRSS1 P07477 1/20 0.38
▸ ACR P10323 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12376954 0.92 KMT2A (0.46) KMT2AMAPTLMNAGAAMAOB
SCHEMBL15164083 0.92 KMT2A (0.46) KMT2AMAPTLMNAGAAMAOB
SCHEMBL12376957 0.91 MAPT (0.47) KMT2AMAPTLMNAGAAMAOB
SCHEMBL13865058 0.86 KMT2A (0.41) KMT2AMAPTTSHRLMNAGAA
SCHEMBL12376996 0.86 SRD5A2 (0.44) KMT2AMAPTMEN1ALDH1A1SMN1; SMN2
SCHEMBL12762437 0.85 LMNA (0.46) KMT2AMAPTLMNAGAAALDH1A1
SCHEMBL139355 0.84 KMT2A (0.39) KMT2AMAPTTSHRLMNAGAA
SCHEMBL16573859 0.83 MAPT (0.46) KMT2AMAPTLMNAGAAMEN1
SCHEMBL14444754 0.83 KMT2A (0.51) KMT2AMAPTGLATSHRLMNA
SCHEMBL12762440 0.83 KMT2A (0.59) KMT2AMAPTGLATSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8874001-B2 Image forming apparatus OKI DATA CORPORATION (JP) 2014-10-28 — — US disclosed
US-20130101313-A1 IMAGE FORMING APPARATUS OKI DATA CORPORATION (JP) 2013-04-25 — — US disclosed
US-7718337-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2010-05-18 — — US disclosed
US-20090081570-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-03-26 — — US disclosed
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