Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12377596 | 0.83 | MTNR1A (0.33) | MTNR1AMTNR1BALDH1A1MAPT | |
| SCHEMBL12377594 | 0.82 | MTNR1A (0.33) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL12377627 | 0.74 | ALDH1A1 (0.40) | MTNR1AMTNR1BSIGMAR1CYP2D6ALDH1A1 | |
| SCHEMBL44266 | 0.67 | MTNR1A (0.42) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL28081835 | 0.67 | RECQL (0.47) | MTNR1AMTNR1BSIGMAR1CYP2D6KDM4E | |
| SCHEMBL18745499 | 0.64 | KDM1A (0.38) | MTNR1AMTNR1BAKT1KDM4EALDH1A1 | |
| SCHEMBL2769676 | 0.63 | KDM1A (0.44) | AKT1ALDH1A1MAPT | |
| SCHEMBL2769679 | 0.63 | KDM1A (0.44) | AKT1ALDH1A1MAPT | |
| SCHEMBL2769683 | 0.63 | KDM1A (0.44) | AKT1ALDH1A1MAPT | |
| SCHEMBL9421170 | 0.63 | PTAFR (0.37) | MTNR1AMTNR1BKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003287-B2 | Low temperature charge transportability and potential, sensitivity and photoresponsiveness; durability | SHARP KABUSHIKI KAISHA (JP) | 2011-08-23 | — | — | US | disclosed |
| US-20080166642-A1 | Electrophotographic photoconductor and image-forming apparatus | SHARP KABUSHIKI KAISHA (JP) | 2008-07-10 | — | — | US | disclosed |