Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28081835 | 0.79 | RECQL (0.47) | ALDH1A1MAPTSIGMAR1MTNR1AMTNR1B | |
| SCHEMBL12422795 | 0.74 | ALDH1A1 (0.40) | ALDH1A1MAPTSIGMAR1MTNR1AMTNR1B | |
| SCHEMBL12377595 | 0.74 | MTNR1A (0.34) | ALDH1A1MAPTSIGMAR1MTNR1AMTNR1B | |
| SCHEMBL28005546 | 0.71 | SIGMAR1 (0.38) | ALDH1A1MAPTSIGMAR1MTNR1AMTNR1B | |
| SCHEMBL28005171 | 0.70 | CYP3A4 (0.55) | HIF1ACYP2D6HPGDCYP1A2CYP2C9 | |
| SCHEMBL28005578 | 0.69 | AOC3 (0.41) | ALDH1A1MAPTSIGMAR1MTNR1AMTNR1B | |
| SCHEMBL3966094 | 0.68 | ALDH1A1 (0.41) | ALDH1A1MAPTKMT2ARAB9ANPC1 | |
| SCHEMBL12377628 | 0.68 | ALDH1A1 (0.36) | ALDH1A1MAPTSIGMAR1MTNR1AMTNR1B | |
| SCHEMBL12422791 | 0.68 | G6PC1 (0.43) | ALDH1A1SIGMAR1KMT2AMEN1 | |
| SCHEMBL496557 | 0.68 | ALDH1A1 (0.44) | ALDH1A1MAPTMTNR1AMTNR1BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003287-B2 | Low temperature charge transportability and potential, sensitivity and photoresponsiveness; durability | SHARP KABUSHIKI KAISHA (JP) | 2011-08-23 | — | — | US | disclosed |
| US-20080166642-A1 | Electrophotographic photoconductor and image-forming apparatus | SHARP KABUSHIKI KAISHA (JP) | 2008-07-10 | — | — | US | disclosed |