Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9520975 | 0.93 | MTNR1A (0.47) | MTNR1AMTNR1BCES2CES1ALDH1A1 | |
| SCHEMBL88322 | 0.87 | ALDH1A1 (0.46) | MTNR1AMTNR1BCES2CES1ALDH1A1 | |
| SCHEMBL183824 | 0.83 | KDM1A (0.42) | MTNR1AMTNR1BCES2CES1ALDH1A1 | |
| SCHEMBL2769679 | 0.80 | KDM1A (0.44) | CES2CES1ALDH1A1TDP1TSHR | |
| SCHEMBL2769683 | 0.80 | KDM1A (0.44) | CES2CES1ALDH1A1TDP1TSHR | |
| SCHEMBL2769676 | 0.80 | KDM1A (0.44) | CES2CES1ALDH1A1TDP1TSHR | |
| SCHEMBL28895073 | 0.78 | CES2 (0.39) | CES2CES1ALDH1A1CYP2C19NPSR1 | |
| SCHEMBL10397770 | 0.78 | AKR1C3 (0.50) | MTNR1AMTNR1BCES2CES1ALDH1A1 | |
| SCHEMBL10397769 | 0.78 | AKR1C3 (0.50) | MTNR1AMTNR1BCES2CES1ALDH1A1 | |
| SCHEMBL23366441 | 0.76 | CES2 (0.38) | MTNR1AMTNR1BCES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9232785-B2 | Method for reducing sunburn damage in plants | BASF SE (DE) | 2016-01-12 | — | — | US | disclosed |
| US-8748347-B2 | Method for combating harmful fungi | BASF SE (DE) | 2014-06-10 | — | — | US | disclosed |
| EP-2584896-A2 | HERBICIDAL COMPOSITIONS | BASF SE (DE) | 2013-05-01 | — | — | EP | disclosed |
| US-20130102463-A1 | Herbicidal Compositions | BASF SE (DE) | 2013-04-25 | — | — | US | disclosed |
| US-20120083497-A1 | Method for Combating Harmful Fungi | BASF SE (DE) | 2012-04-05 | — | — | US | disclosed |
| EP-2418944-A2 | METHOD FOR COMBATING HARMFUL FUNGI | BASF SE (DE) | 2012-02-22 | — | — | EP | disclosed |
| EP-2413691-A2 | METHOD FOR REDUCING SUNBURN DAMAGE IN PLANTS | BASF SE (DE) | 2012-02-08 | — | — | EP | disclosed |
| US-20120017503-A1 | METHOD FOR REDUCING SUNBURN DAMAGE IN PLANTS | BASF SE (DE) | 2012-01-26 | — | — | US | disclosed |
| WO-2011161105-A2 | HERBICIDAL COMPOSITIONS | BASF SE (DE) | 2011-12-29 | — | — | WO | disclosed |
| WO-2010115721-A2 | METHOD FOR REDUCING SUNBURN DAMAGE IN PLANTS | BASF SE (DE) | 2010-10-14 | — | — | WO | disclosed |
| WO-2010115720-A2 | METHOD FOR COMBATING HARMFUL FUNGI | BASF SE (DE) | 2010-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102463-A1 | Herbicidal Compositions | PPOX, PAOX, DDT | MTNR1A 1941/4885MTNR1B 981/4885CES2 392/4885 |
| US-20120017503-A1 | METHOD FOR REDUCING SUNBURN DAMAGE IN PLANTS | UNG, ERCC5, ERCC4 | MTNR1A 1168/4885MTNR1B 1437/4885CES2 1204/4885 |
| US-20120083497-A1 | Method for Combating Harmful Fungi | BROX, CRY1, GUSB | MTNR1A 688/4885MTNR1B 896/4885CES2 3118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.