Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | DBH | P09172 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 6/20 | 0.37 |
| ▸ | CA1 | P00915 | 6/20 | 0.37 |
| ▸ | CA2 | P00918 | 6/20 | 0.37 |
| ▸ | CA7 | P43166 | 6/20 | 0.37 |
| ▸ | CA9 | Q16790 | 6/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | FUT7 | Q11130 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA6 | P23280 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357899 | 0.84 | KDM4E (0.63) | KDM4EGAADBHRECQLFFAR1 | |
| SCHEMBL17718140 | 0.81 | KDM4E (0.55) | KDM4EGAADBHRECQLFFAR1 | |
| SCHEMBL22889592 | 0.80 | KDM4E (0.59) | KDM4EGAADBHRECQLFFAR1 | |
| SCHEMBL9962964 | 0.80 | GAA (0.56) | KDM4EGAADBHRECQLFFAR1 | |
| SCHEMBL12088398 | 0.79 | KDM4E (0.47) | KDM4EGAADBHRECQLFFAR1 | |
| SCHEMBL15631135 | 0.77 | KDM4E (0.55) | KDM4EGAADBHRECQLFFAR1 | |
| SCHEMBL16256439 | 0.76 | KDM4E (0.54) | KDM4EGAADBHRECQLFFAR1 | |
| SCHEMBL7507075 | 0.76 | TPMT (0.54) | KDM4EGAADBHRECQLFFAR1 | |
| SCHEMBL8471397 | 0.76 | KDM4E (1.00) | KDM4EGAADBHRECQLFFAR1 | |
| SCHEMBL22889639 | 0.75 | GAA (0.53) | KDM4EGAADBHRECQLFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969303-B2 | Tocotrienol esters | FIRST TECH INTERNATIONAL LIMITED (CN) | 2015-03-03 | — | — | US | disclosed |
| US-20110196030-A1 | TOCOTRIENOL ESTERS | FIRST TECH INTERNATIONAL LIMITED (CN) | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110196030-A1 | TOCOTRIENOL ESTERS | TTPA, MBOAT1, TBXAS1 | KDM4E 1182/4885GAA 3587/4885DBH 2908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.