SCHEMBL6357899

SCHEMBL6357899

CC(C)C(=O)c1cc(O)c(O)c(O)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.63
GAA P10253 3/20 0.63
RECQL P46063 2/20 0.63
DBH P09172 1/20 0.63
FFAR1 O14842 1/20 0.56
LMNA P02545 3/20 0.52
TDP1 Q9NUW8 3/20 0.52
FUT7 Q11130 2/20 0.52
ALDH1A1 P00352 2/20 0.52
MAPT P10636 2/20 0.52
SELL P14151 2/20 0.52
SELP P16109 2/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
TP53 P04637 1/20 0.52
CA3 P07451 1/20 0.52
HPGD P15428 1/20 0.52
FUT4 P22083 1/20 0.52
CA4 P22748 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17718140 0.87 KDM4E (0.55) KDM4EGAARECQLDBHFFAR1
SCHEMBL15631135 0.87 KDM4E (0.55) KDM4EGAARECQLDBHFFAR1
SCHEMBL22889639 0.86 GAA (0.53) KDM4EGAARECQLDBHFFAR1
SCHEMBL15631140 0.86 KDM4E (0.53) KDM4EGAARECQLDBHFFAR1
SCHEMBL12377739 0.84 KDM4E (0.61) KDM4EGAARECQLDBHFFAR1
SCHEMBL14339416 0.84 POLB (0.65) KDM4EGAARECQLDBHFFAR1
SCHEMBL14339417 0.84 POLB (0.55) KDM4EGAARECQLDBHFFAR1
SCHEMBL22889592 0.82 KDM4E (0.59) KDM4EGAARECQLDBHFFAR1
SCHEMBL9962964 0.82 GAA (0.56) KDM4EGAARECQLDBHFFAR1
SCHEMBL7374206 0.80 TTR (0.57) KDM4EGAARECQLDBHLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230346864-A1 Compositions and Methods for Joint Health INNOPHOS, LLC (US) 2023-11-02 US disclosed
US-20230346864-A1 Compositions and Methods for Joint Health INNOPHOS, LLC (US) 2023-11-02 US disclosed
US-11793823-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-10-24 US disclosed
US-11779561-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-10-10 US disclosed
US-11779561-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-10-10 US disclosed
US-20230119068-A1 METHODS FOR RAPID SYNTHESIS OF PYRANOANTHOCYANINS OHIO STATE INNOVATION FOUNDATION 2023-04-20 US disclosed
US-20220388968-A1 INHIBITORS OF ERYTHROCYTE BAND 3 TYROSINE PHOSPHORYLATION AND USES THEREOF PURDUE RESEARCH FOUNDATION 2022-12-08 US disclosed
US-11382924-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2022-07-12 US disclosed
US-11358985-B2 Tripeptide compound, preparation method therefor, and application thereof NORTHWEST UNIVERSITY (CN) 2022-06-14 US disclosed
US-20220152069-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2022-05-19 US disclosed
US-20130143925-A1 ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-06-06 US disclosed
US-8367677-B2 Comprising trihydroxy phenyl subunits; selectin inhibitors; side effect reduction; 3-{3-[3-(3,4,5-Trihydroxy-phenyl)-propionylamino]-phenylamino}-benzoic acid REVOTAR BIOPHARMACEUTICALS AG (DE) 2013-02-05 US disclosed
US-20120121536-A1 COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION OHIO UNIVERSITY (US) 2012-05-17 US disclosed
US-20120121536-A1 COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION OHIO UNIVERSITY (US) 2012-05-17 US disclosed
US-20110065662-A1 Compounds, Compositions, and Methods for Protecting Brain Health in Neurodegenerative Disorders AMAZENTIS SA (CH) 2011-03-17 US disclosed
US-20110065662-A1 Compounds, Compositions, and Methods for Protecting Brain Health in Neurodegenerative Disorders AMAZENTIS SA (CH) 2011-03-17 US disclosed
US-20090062186-A1 Compounds Binding To P-Selectin YAMANOUCHI ERUOPE B.V. (NL) 2009-03-05 US disclosed
US-20080249107-A1 Non-Glycosylated/Non-Glycosidic/Non-Peptidic Small Molecule Psgl-1 Mimetics for the Treatment of Inflammatory Disorders REVOTAR BIOPHARMACEUTICALS AG (DE) 2008-10-09 US disclosed
US-20070282422-A1 Medical devices and methods for local delivery of elastin-stabilizing compounds COOK INCORPORATED 2007-12-06 US disclosed
US-20070282422-A1 Medical devices and methods for local delivery of elastin-stabilizing compounds COOK INCORPORATED 2007-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11358985-B2 Tripeptide compound, preparation method therefor, and application thereof VIP, PREP, ACE KDM4E 4263/4885GAA 923/4885RECQL 4409/4885
US-20090062186-A1 Compounds Binding To P-Selectin SELP, SELPLG, SELL KDM4E 4770/4885GAA 1825/4885RECQL 3108/4885
US-20110065662-A1 Compounds, Compositions, and Methods for Protecting Brain Health in Neurodegenerative Disorders HTT, BDNF, PYGB KDM4E 640/4885GAA 73/4885RECQL 908/4885
US-20120121536-A1 COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION SLC2A1, SLC2A4, SLC2A3 KDM4E 2744/4885GAA 515/4885RECQL 4575/4885
US-20130143925-A1 ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE EPHX1, FAAH, FAAH2 KDM4E 921/4885GAA 635/4885RECQL 1665/4885
US-20220152069-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF ACE, ACE2, FURIN KDM4E 4466/4885GAA 242/4885RECQL 1538/4885
US-20230346864-A1 Compositions and Methods for Joint Health MMP14, MMP13, MMP1 KDM4E 1693/4885GAA 735/4885RECQL 543/4885
US-20230119068-A1 METHODS FOR RAPID SYNTHESIS OF PYRANOANTHOCYANINS HCCS, PPOX, RNGTT KDM4E 2442/4885GAA 1503/4885RECQL 588/4885
US-20220388968-A1 INHIBITORS OF ERYTHROCYTE BAND 3 TYROSINE PHOSPHORYLATION AND USES THEREOF SPTBN1, CTTN, HBG1 KDM4E 2947/4885GAA 1738/4885RECQL 1377/4885
US-11382924-B2 Compounds and pharmaceutical uses thereof ACE, ACE2, FURIN KDM4E 4466/4885GAA 242/4885RECQL 1538/4885
US-11779561-B2 Compounds and pharmaceutical uses thereof ACE, ACE2, FURIN KDM4E 4466/4885GAA 242/4885RECQL 1538/4885
US-20080249107-A1 Non-Glycosylated/Non-Glycosidic/Non-Peptidic Small Molecule Psgl-1 Mimetics for the Treatment of Inflammatory Disorders SELP, SELPLG, SELE KDM4E 4259/4885GAA 2954/4885RECQL 4093/4885
US-11793823-B2 Compounds and pharmaceutical uses thereof HRH4, OR10J3, CYP3A5 KDM4E 2317/4885GAA 1734/4885RECQL 1033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.