SCHEMBL12377817

SCHEMBL12377817

c1ccc(-n2c3ccccc3c3ccc4c5ccccc5n(-c5ccc(C6(c7cccc(-n8c9ccccc9c9ccc%10c%11ccccc%11n(-c%11ccccc%11)c%10c98)c7)c7ccccc7-c7ccccc76)cc5)c4c32)cc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
OPRK1 P41145 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
DUSP3 P51452 1/20 0.35
PTPN1 P18031 1/20 0.32
POLB P06746 1/20 0.31
MAPK8 P45983 1/20 0.30
MAPK9 P45984 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10029957 0.92 KDM4E (0.47) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL12104886 0.92 KDM4E (0.41) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL18086265 0.91 KDM4E (0.41) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL1298551 0.91 KDM4E (0.41) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL12104887 0.89 KDM4E (0.44) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL14718357 0.88 KDM4E (0.49) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL29990483 0.88 KDM4E (0.49) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL1298715 0.87 KDM4E (0.41) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL10029942 0.87 L3MBTL1 (0.45) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL12104933 0.86 KDM4E (0.38) KDM4EATML3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8994008-B2 Reverse printing ink composition, printing method using the same, method of manufacturing display unit using the same SONY CORPORATION (JP) 2015-03-31 US disclosed
US-8994008-B2 Reverse printing ink composition, printing method using the same, method of manufacturing display unit using the same SONY CORPORATION (JP) 2015-03-31 US disclosed
US-20120252300-A1 REVERSE PRINTING INK COMPOSITION, PRINTING METHOD USING THE SAME, METHOD OF MANUFACTURING DISPLAY UNIT USING THE SAME SONY CORPORATION (JP) 2012-10-04 US disclosed
US-20120252300-A1 REVERSE PRINTING INK COMPOSITION, PRINTING METHOD USING THE SAME, METHOD OF MANUFACTURING DISPLAY UNIT USING THE SAME SONY CORPORATION (JP) 2012-10-04 US disclosed
US-7993760-B2 Compound for use in organic electroluminescent device and organic electroluminescent device NIPPON STEEL CHEMICAL CO., LTD. (JP) 2011-08-09 US disclosed
US-7993760-B2 Compound for use in organic electroluminescent device and organic electroluminescent device NIPPON STEEL CHEMICAL CO., LTD. (JP) 2011-08-09 US disclosed
US-20090302742-A1 Compound for Use in Organic Electroluminescent Device and Organic Electroluminescent Device NIPPON STEEL CHEMICAL CO., LTD. (JP) 2009-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090302742-A1 Compound for Use in Organic Electroluminescent Device and Organic Electroluminescent Device LAGE3, ICMT, PPOX KDM4E 2976/4885ATM 3133/4885L3MBTL1 1565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.