Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12378763 | 0.84 | TDP1 (0.59) | ALDH1A1SMN1; SMN2LMNATP53MEN1 | |
| SCHEMBL13266932 | 0.84 | TSHR (0.54) | ALDH1A1SMN1; SMN2SRD5A2CES2CES1 | |
| SCHEMBL12378742 | 0.81 | LMNA (0.41) | SMN1; SMN2LMNAMEN1KMT2ATSHR | |
| SCHEMBL22472195 | 0.80 | TSHR (0.59) | SRD5A2CES2CES1TP53RXRA | |
| Terephthalic Acid SCHEMBL15994297 | 0.78 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2SRD5A2CES2CES1 | |
| SCHEMBL31192242 | 0.78 | TSHR (0.60) | ALDH1A1SMN1; SMN2SRD5A2CES2CES1 | |
| 4-Methylbenzoic Acid SCHEMBL14723409 | 0.78 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2SRD5A2CES2CES1 | |
| 4-Methylbenzoic Acid SCHEMBL7940172 | 0.78 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2SRD5A2CES2CES1 | |
| SCHEMBL12378739 | 0.78 | CYP2D6 (0.56) | ALDH1A1SMN1; SMN2LMNATSHRL3MBTL1 | |
| 4-Methylbenzoic Acid SCHEMBL27936299 | 0.78 | ALDH1A1 (0.94) | ALDH1A1SMN1; SMN2SRD5A2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994372-B2 | Parylene variants and methods of synthesis and use | SPECIALTY COATING SYSTEMS, INC. (US) | 2011-08-09 | — | — | US | disclosed |
| US-20090186998-A1 | PARYLENE VARIANTS AND METHODS OF SYNTHESIS AND USE | SPECIALTY COATING SYSTEMS, INC. (US) | 2009-07-23 | — | — | US | disclosed |
| US-7462750-B2 | Parylene variants and methods of synthesis and use | SPECIALTY COATING SYSTEMS, INC. (US) | 2008-12-09 | — | — | US | disclosed |
| US-20070099019-A1 | Parylene variants and methods of synthesis and use | SPECIALTY COATING SYSTEMS, INC. (US) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099019-A1 | Parylene variants and methods of synthesis and use | CDC73, PARN, PFAS | ALDH1A1 3048/4885SMN1; SMN2 3821/4885SRD5A2 3557/4885 |
| US-20090186998-A1 | PARYLENE VARIANTS AND METHODS OF SYNTHESIS AND USE | CDC73, PARN, PFAS | ALDH1A1 2365/4885SMN1; SMN2 3835/4885SRD5A2 3548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.