Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.56 |
| ▸ | ACACA | Q13085 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12379281 | 0.89 | ACACB (0.59) | ACACBACACASRD5A2LTA4HATM | |
| SCHEMBL2295053 | 0.83 | CTSS (0.52) | ACACBACACASRD5A2MEN1KMT2A | |
| SCHEMBL17483401 | 0.80 | NPC1 (0.48) | ACACBMEN1KMT2ALTA4HATM | |
| SCHEMBL5225218 | 0.80 | KMT2A (0.62) | MEN1KMT2AATMGPR88 | |
| SCHEMBL1712333 | 0.80 | KMT2A (0.62) | MEN1KMT2AATMGPR88 | |
| SCHEMBL8273800 | 0.80 | KMT2A (0.62) | MEN1KMT2AATMGPR88 | |
| Hydrochloric Acid SCHEMBL5223983 | 0.78 | KMT2A (0.60) | MEN1KMT2A | |
| SCHEMBL9082510 | 0.78 | KMT2A (0.68) | MEN1KMT2AATMPPARGPPARA | |
| SCHEMBL20240307 | 0.78 | LTA4H (0.53) | ACACBACACASRD5A2LTA4HPPARG | |
| SCHEMBL17727241 | 0.77 | ROCK2 (0.48) | ACACBMEN1KMT2AATMCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989480-B2 | Aryl amino acid derivatives as inhibitors for treating inflammation | DECODE GENETICS EHF (IS) | 2011-08-02 | — | — | US | disclosed |
| US-20080033024-A1 | ARYL AMINO ACID DERIVATIVES AS INHIBITORS FOR TREATING INFLAMMATION | DECODE GENETICS EHF. (IS) | 2008-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080033024-A1 | ARYL AMINO ACID DERIVATIVES AS INHIBITORS FOR TREATING INFLAMMATION | LTA4H, LTB4R2, LTB4R | ACACB 1829/4885ACACA 1249/4885SRD5A2 1780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.