SCHEMBL12379541

SCHEMBL12379541

CCCCCCCc1cccc(N(C)c2ccc(-c3ccc(-c4ccc(C)cc4)cc3)cc2)c1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LPL P06858 2/20 0.43
LIPG Q9Y5X9 2/20 0.43
PPARG P37231 3/20 0.39
PPARA Q07869 3/20 0.39
RARB P10826 3/20 0.39
KCNH2 Q12809 1/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12379547 1.00 LPL (0.43) LPLLIPGPPARGPPARARARB
SCHEMBL12619764 0.95 LPL (0.40) LPLLIPGPPARGPPARARARB
SCHEMBL12379542 0.90 LPL (0.39) LPLLIPGPPARGPPARAKCNH2
SCHEMBL12379553 0.86 HSD17B10 (0.51) LPLLIPGRARBTSHRHSD17B10
SCHEMBL12619459 0.86 HSD17B10 (0.51) LPLLIPGRARBTSHRHSD17B10
SCHEMBL12619873 0.84 LPL (0.53) LPLLIPGPPARGPPARAKCNH2
SCHEMBL12379573 0.84 HSD11B1 (0.40) RARBKCNH2TSHRHSD17B10
SCHEMBL15854837 0.84 LPL (0.45) LPLLIPGPPARGPPARARARB
SCHEMBL12619731 0.84 HSD11B1 (0.48) RARBKCNH2TSHRHSD17B10
SCHEMBL12619714 0.84 SIGMAR1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110198573-A1 CHARGE-TRANSPORTING POLYMER, COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC EL DISPLAY, AND ORGANIC EL LIGHTING MITSUBISHI CHEMICAL CORPORATION (JP) 2011-08-18 US disclosed