Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 2/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | RORA | P35398 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12379547 | 0.90 | LPL (0.43) | LPLLIPGKCNH2PPARGPPARA | |
| SCHEMBL12379541 | 0.90 | LPL (0.43) | LPLLIPGKCNH2PPARGPPARA | |
| SCHEMBL12379568 | 0.87 | CTSV (0.41) | CTSVCTSLKCNH2HSD11B1RORA | |
| SCHEMBL12379488 | 0.86 | SIGMAR1 (0.33) | DRD2SLC6A2HTR2AHTR2CSLC6A4 | |
| SCHEMBL12619764 | 0.85 | LPL (0.40) | LPLLIPGPPARGPPARAHSD11B1 | |
| SCHEMBL12619659 | 0.80 | CYP2C19 (0.36) | SIGMAR1 | |
| SCHEMBL12379518 | 0.79 | MLNR (0.38) | CTSVCTSLDRD2SLC6A2HTR2A | |
| SCHEMBL12619873 | 0.78 | LPL (0.53) | LPLLIPGKCNH2PPARGPPARA | |
| SCHEMBL12379573 | 0.78 | HSD11B1 (0.40) | KCNH2SIGMAR1HSD11B1 | |
| SCHEMBL12619731 | 0.78 | HSD11B1 (0.48) | KCNH2HTR2ASIGMAR1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110198573-A1 | CHARGE-TRANSPORTING POLYMER, COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC EL DISPLAY, AND ORGANIC EL LIGHTING | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-08-18 | — | — | US | disclosed |