Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.62 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | TDO2 | P48775 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.49 |
| ▸ | TUBB | P07437 | 2/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2292369 | 0.88 | CYP19A1 (0.71) | CYP19A1MEN1KMT2ACYP3A4CYP1A2 | |
| SCHEMBL30129997 | 0.88 | CYP19A1 (0.71) | CYP19A1MEN1KMT2ACYP3A4CYP1A2 | |
| SCHEMBL14071710 | 0.84 | CYP19A1 (0.82) | CYP19A1MEN1KMT2ACYP3A4CYP1A2 | |
| SCHEMBL10328456 | 0.84 | CYP19A1 (0.65) | CYP19A1MEN1KMT2ACYP3A4CYP1A2 | |
| SCHEMBL11860502 | 0.81 | CYP19A1 (0.58) | CYP19A1MEN1KMT2ACYP3A4CYP1A2 | |
| SCHEMBL11857614 | 0.81 | CYP19A1 (0.58) | CYP19A1MEN1KMT2ACYP3A4CYP1A2 | |
| SCHEMBL9730692 | 0.80 | MEN1 (0.67) | CYP19A1MEN1KMT2ACYP3A4ALOX5 | |
| SCHEMBL11854982 | 0.80 | CYP19A1 (0.54) | CYP19A1MEN1KMT2ACYP3A4NFKB1 | |
| SCHEMBL6339281 | 0.79 | ALOX5 (0.77) | CYP19A1MEN1KMT2ACYP3A4CYP1A2 | |
| SCHEMBL11855540 | 0.78 | CYP19A1 (0.57) | CYP19A1MEN1KMT2ACYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8992892-B2 | Use of 1-(2,4-dihydroxy-phenyl)-3-(3-hydroxy-4-methoxy-phenyl)-propan-1-one | SYMRISE AG (DE) | 2015-03-31 | — | — | US | disclosed |
| US-20110189108-A1 | USE OF 1-(2,4-DIHYDROXY-PHENYL)-3-(3-HYDROXY-4-METHOXY-PHENYL)-PROPAN-1-ONE | SYMRISE AG (DE) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110189108-A1 | USE OF 1-(2,4-DIHYDROXY-PHENYL)-3-(3-HYDROXY-4-METHOXY-PHENYL)-PROPAN-1-ONE | HES1, TAS2R20, TAS2R50 | CYP19A1 4353/4885IDO1 2270/4885TDO2 4111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.