Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 3/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,3-Propanediol SCHEMBL2865031 | 0.92 | FBP1 (0.36) | ALDH1A1TSHRAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL2221643 | 0.84 | ALDH1A1 (0.39) | ALDH1A1TSHRAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL2863424 | 0.82 | MEN1 (0.42) | ALDH1A1TSHRAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL1304100 | 0.80 | CYP2A6 (0.38) | ALDH1A1AKR1C3CYP3A4KMT2A | |
| SCHEMBL4275844 | 0.79 | MEN1 (0.40) | ALDH1A1TSHRAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL2362850 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TSHRAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL17685853 | 0.76 | ALDH1A1 (0.52) | ALDH1A1TSHRCYP3A4TP53LMNA | |
| SCHEMBL7031297 | 0.73 | ALDH1A1 (0.41) | ALDH1A1TSHRAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL12593472 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TSHRAKR1C3AKR1C1ESR1 | |
| SCHEMBL14765003 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TSHRAKR1C3AKR1C1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63264411-A | — | — | None | — | — | JP | disclosed |
| US-9777034-B2 | Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2017-10-03 | — | — | US | disclosed |
| US-9623046-B2 | Amphiphilic Janus-dendrimers | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2017-04-18 | — | — | US | disclosed |
| US-20160108076-A1 | MODULAR SYNTHESIS OF AMPHIPHILIC JANUS GLYCODENDRIMERS AND THEIR SELF-ASSEMBLY INTO GLYCODENDRIMERSOMES | NATIONAL SCIENCE FOUNDATION | 2016-04-21 | — | — | US | disclosed |
| CN-105408300-A | Method for producing (meth) acryloyl group-containing polyol compound, (meth) acryloyl group-containing polyol compound, and urethane (meth) acrylate | DAINIPPON INK & CHEMICALS | 2016-03-16 | — | — | CN | disclosed |
| WO-2015000123-A1 | METHOD FOR MANUFACTURING (METH)ACRYLOYL GROUP-CONTAINING POLYOL COMPOUND, (METH)ACRYLOYL GROUP-CONTAINING POLYOL COMPOUND, AND URETHANE (METH)ACRYLATE | DIC CORPORATION (JP) | 2015-01-08 | — | — | WO | disclosed |
| WO-2014190024-A1 | MODULAR SYNTHESIS OF AMPHIPHILIC JANUS GLYCODENDRIMERS AND THEIR SELF-ASSEMBLY INTO GLYCODENDRIMERSOMES | PERCEC VIRGIL (US) | 2014-11-27 | — | — | WO | disclosed |
| US-20120308640-A1 | AMPHIPHILIC JANUS-DENDRIMERS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-12-06 | — | — | US | disclosed |
| US-8318795-B2 | Antioxidant polymers containing [1,2]-dithiolane moieties and uses thereof | CEDARS-SINAI MEDICAL CENTER (US) | 2012-11-27 | — | — | US | disclosed |
| CN-101341119-B | Higher fatty acid triester and amide derivative having diethylenetriamine-type metal chelate structure | FUJI PHOTO FILM CO LTD | 2012-06-27 | — | — | CN | disclosed |
| WO-2007072983-A1 | HIGHER FATTY ACID TRIESTER AND AMIDE DERIVATIVE HAVING DIETHYLENETRIAMINE-TYPE METAL CHELATE STRUCTURE | FUJIFILM CORPORATION (JP) | 2007-06-28 | — | — | WO | disclosed |
| US-5102895-A | Antilipemic agent having a number of nicotinic acid molecule bonded to vitamin; synergistic, side effect reduction | EISAI CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0436911-A2 | Novel vitamin E derivatives and process for the production thereof | Eisai Co., Ltd. (JP) | 1991-07-17 | — | — | EP | disclosed |
| CN-1053062-A | Novel vitamin E derivatives and process for preparing the same | EISAI CO LTD (JP) | 1991-07-17 | — | — | CN | disclosed |
| EP-0309248-A2 | Acrylated diols | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-03-29 | — | — | EP | disclosed |
| JP-S63264411-A | CARCINOSTATIC AGENT | RIKAGAKU KENKYUSHO | 1988-11-01 | — | — | JP | disclosed |
| EP-0148094-A2 | Anti-tumor agent comprising an O-benzylidene-L-ascorbic acid or a salt thereof, and the production of the latter compound | Kochi, Mutsuyuki (JP) | 1985-07-10 | — | — | EP | disclosed |
| EP-0123679-A1 | ESTERS OF RETINOIC ACID AND PENTAERYTHRITOL AND MONOBENZAL ACETALS THEREOF | SRI INTERNATIONAL (US) | 1984-11-07 | — | — | EP | disclosed |
| US-4464389-A | SKIN DISORDERS, ANTITUMOR AGENTS | SRI INTERNATIONAL (US) | 1984-08-07 | — | — | US | disclosed |
| WO-1984001573-A1 | ESTERS OF RETINOIC ACID AND PENTAERYTHRITOL AND MONOBENZAL ACETALS THEREOF | STANFORD RES INST INT (US) | 1984-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120308640-A1 | AMPHIPHILIC JANUS-DENDRIMERS | OR10J3, H1-10, CXCR3 | ALDH1A1 4511/4885TSHR 852/4885AKR1C3 2325/4885 |
| US-20160108076-A1 | MODULAR SYNTHESIS OF AMPHIPHILIC JANUS GLYCODENDRIMERS AND THEIR SELF-ASSEMBLY INTO GLYCODENDRIMERSOMES | C1S, PYM1, DEGS1 | ALDH1A1 1539/4885TSHR 1820/4885AKR1C3 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.