Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,3-Propanediol SCHEMBL4275144 | 0.94 | MEN1 (0.39) | MEN1KMT2AAKR1C3RECQLNR1I2 | |
| SCHEMBL4275844 | 0.86 | MEN1 (0.40) | MEN1KMT2AAKR1C3RECQLNR1I2 | |
| SCHEMBL1238436 | 0.82 | ALDH1A1 (0.40) | MEN1KMT2AAKR1C3RECQLNR1I2 | |
| 1,3-Propanediol SCHEMBL2865031 | 0.75 | FBP1 (0.36) | MEN1KMT2AAKR1C3RECQLNR1I2 | |
| SCHEMBL2221643 | 0.73 | ALDH1A1 (0.39) | MEN1KMT2AAKR1C3RECQLNR1I2 | |
| SCHEMBL28085114 | 0.70 | ALDH1A1 (0.52) | KMT2AALDH1A1TSHRLMNATDP1 | |
| Benzene SCHEMBL7029282 | 0.70 | GRM2 (0.32) | MEN1KMT2AALDH1A1TSHR | |
| Phenol SCHEMBL10925725 | 0.70 | CA12 (0.46) | ALDH1A1CYP3A4LMNATDP1 | |
| SCHEMBL1304100 | 0.70 | CYP2A6 (0.38) | KMT2AAKR1C3ALDH1A1CYP3A4NPC1 | |
| SCHEMBL2362850 | 0.68 | ALDH1A1 (0.39) | MEN1KMT2AAKR1C3RECQLNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318795-B2 | Antioxidant polymers containing [1,2]-dithiolane moieties and uses thereof | CEDARS-SINAI MEDICAL CENTER (US) | 2012-11-27 | — | — | US | disclosed |
| US-20100098653-A1 | ANTIOXIDANT POLYMERS CONTAINING [1,2]-DITHIOLANE MOIETIES AND USES THEREOF | CEDARS-SINAI MEDICAL CENTER (US) | 2010-04-22 | — | — | US | disclosed |
| EP-2125775-A1 | ANTIOXIDANT POLYMERS CONTAINING [1,2]-DITHIOLANE MOIETIES AND USES THEREOF | Cedars-Sinai Medical Center (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008106640-A1 | ANTIOXIDANT POLYMERS CONTAINING [1,2]-DITHIOLANE MOIETIES AND USES THEREOF | CEDARS-SINAI MEDICAL CENTER (US) | 2008-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100098653-A1 | ANTIOXIDANT POLYMERS CONTAINING [1,2]-DITHIOLANE MOIETIES AND USES THEREOF | GPX1, GPX4, LPO | MEN1 4209/4885KMT2A 4539/4885AKR1C3 939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.