Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 2/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CPT1A | P50416 | 4/20 | 0.39 |
| ▸ | CPT1B | Q92523 | 4/20 | 0.39 |
| ▸ | CPT2 | P23786 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12389888 | 0.90 | MEN1 (0.45) | APLNRRAB9AALDH1A1 | |
| SCHEMBL12389015 | 0.87 | LMNA (0.49) | CA12CA1CA2CA4CA6 | |
| SCHEMBL12389028 | 0.86 | LMNA (0.44) | SRD5A1SRD5A2CA12CA1CA2 | |
| SCHEMBL12390239 | 0.85 | HTR2B (0.44) | — | |
| SCHEMBL12365698 | 0.84 | SRD5A2 (0.51) | SRD5A1SRD5A2TTRMRGPRX4ALDH1A1 | |
| SCHEMBL12390182 | 0.84 | SRD5A2 (0.46) | SRD5A1SRD5A2TTRMRGPRX4CA12 | |
| SCHEMBL12365335 | 0.84 | SRD5A2 (0.54) | SRD5A1SRD5A2TTRPYGLRAB9A | |
| SCHEMBL12389785 | 0.83 | CYP11B1 (0.40) | MRGPRX4CA12CA1CA2CA4 | |
| SCHEMBL12365317 | 0.82 | SRD5A2 (0.51) | SRD5A1SRD5A2TTRMRGPRX4ALDH1A1 | |
| SCHEMBL12365786 | 0.82 | SRD5A2 (0.48) | SRD5A1SRD5A2TTRMRGPRX4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207729-A1 | BICYCLIC ACYLGUANIDINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207729-A1 | BICYCLIC ACYLGUANIDINE DERIVATIVE | HTR5A, HTR2A, HTR1E | SRD5A1 247/4885SRD5A2 412/4885TTR 3588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.