SCHEMBL1239712

SCHEMBL1239712

C=Cc1ccc(S(=O)(=O)OCC)c2c1-c1ccccc1-2

nearest known ligand 0.30

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
APAF1 O14727 1/20 0.30
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
THRB P10828 1/20 0.30
CASP1 P29466 1/20 0.30
BRCA1 P38398 1/20 0.30
CASP7 P55210 1/20 0.30
KMT2A Q03164 1/20 0.30
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL314320 0.79 ALDH1A1 (0.35) MAPTKDM4EMEN1ALDH1A1GAA
SCHEMBL313316 0.79 ALDH1A1 (0.38) ALDH1A1GAA
SCHEMBL1239717 0.77
SCHEMBL26965297 0.74 PTPN1 (0.34) ALDH1A1
SCHEMBL26025627 0.72 MCL1 (0.36) ALDH1A1TDP1
SCHEMBL1239697 0.71 L3MBTL1 (0.40) MAPTKDM4EALDH1A1GAAMAPK1
SCHEMBL1240284 0.71 TSHR (0.38) MAPTKDM4EALDH1A1TDP1L3MBTL1
SCHEMBL29415266 0.70 GAA (0.39) MEN1ALDH1A1GAAKMT2AMAPK1
SCHEMBL778991 0.70 GAA (0.39) MEN1ALDH1A1GAAKMT2AMAPK1
SCHEMBL1239681 0.70 SMN1; SMN2 (0.39) MAPTMEN1ALDH1A1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7892694-B2 Electrolytic membrane, process for producing the same, membrane electrode assembly, fuel cell and method of operating the same KABUSHIKI KAISHA TOSHIBA (JP) 2011-02-22 US disclosed
CN-1990525-B Electrolytic membrane, process for producing the same, membrane electrode assembly, fuel cell and method of operating the same TOSHIBA CORP 2010-12-08 CN disclosed
US-20070166590-A1 ELECTROLYTIC MEMBRANE, PROCESS FOR PRODUCING THE SAME, MEMBRANE ELECTRODE ASSEMBLY, FUEL CELL AND METHOD OF OPERATING THE SAME KABUSHIKI KAISHA TOSHIBA (JP) 2007-07-19 US disclosed
CN-1990525-A Electrolytic membrane, process for producing the same, membrane electrode assembly, fuel cell and method of operating the same TOSHIBA KK (JP) 2007-07-04 CN disclosed