Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9883889 | 0.87 | ALDH1A1 (0.44) | MEN1KMT2AHTTANTXR2MAOA | |
| SCHEMBL13527164 | 0.86 | ANTXR2 (0.40) | MEN1KMT2AHTTANTXR2MAOA | |
| SCHEMBL10309265 | 0.80 | MAPT (0.38) | MEN1KMT2AHTTANTXR2MAOA | |
| SCHEMBL8316423 | 0.80 | ALOX15 (0.41) | MEN1KMT2AHTTMAOACA1 | |
| SCHEMBL15450054 | 0.79 | TSHR (0.50) | MEN1KMT2AANTXR2ALDH1A1MAPT | |
| SCHEMBL17131537 | 0.77 | ELANE (0.41) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL16485425 | 0.76 | RXRA (0.43) | HTTALDH1A1GAAMAPK1ELANE | |
| SCHEMBL16485023 | 0.76 | L3MBTL1 (0.40) | HTTMAPTGAAL3MBTL1LMNA | |
| SCHEMBL13002657 | 0.75 | MAPT (0.36) | MEN1KMT2AHTTANTXR2MAOA | |
| SCHEMBL12269934 | 0.74 | MAOB (0.44) | MEN1KMT2AHTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334300-B2 | C2-phenyl-substituted cyclic ketonols | BAYER AKTIENGESELLSHAFT (DE) | 2012-12-18 | — | — | US | disclosed |
| US-20110183849-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | BAYER AKTIENGESELLSCHAFT (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183849-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | AKR1C3, PDHX, AKR1C2 | MEN1 4025/4885KMT2A 844/4885HTT 4083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.