SCHEMBL12403146

SCHEMBL12403146

OCCN(CCO)CC(O)COc1ccc(C(c2ccc(OCC(O)CN(CCO)CCO)cc2)c2ccc(OCC(O)CN(CCO)CCO)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 5/20 0.64
▸ ALDH1A1 P00352 4/20 0.63
▸ LMNA P02545 1/20 0.63
▸ NCOA3 Q9Y6Q9 1/20 0.57
▸ MAPK1 P28482 2/20 0.56
▸ MAPT P10636 1/20 0.56
▸ KDM4E B2RXH2 2/20 0.54
▸ TDP1 Q9NUW8 1/20 0.54
▸ NPSR1 Q6W5P4 1/20 0.49
▸ TSHR P16473 2/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ POLB P06746 1/20 0.43
▸ HTT P42858 1/20 0.42
▸ HIF1A Q16665 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31414645 0.84 ALDH1A1 (0.67) GAAALDH1A1LMNANCOA3MAPK1
SCHEMBL31414644 0.84 ALDH1A1 (0.67) GAAALDH1A1LMNANCOA3MAPK1
SCHEMBL11672344 0.81 MAPK1 (0.69) GAAALDH1A1LMNANCOA3MAPK1
SCHEMBL759782 0.81 ALDH1A1 (0.67) GAAALDH1A1LMNANCOA3MAPK1
SCHEMBL9636165 0.81 ALDH1A1 (0.62) GAAALDH1A1LMNANCOA3MAPK1
SCHEMBL6018530 0.79 MAPK1 (0.55) GAAALDH1A1LMNANCOA3MAPK1
SCHEMBL16314644 0.78 GAA (0.47) GAAALDH1A1LMNANCOA3MAPK1
SCHEMBL31213834 0.78 AR (0.53) ALDH1A1LMNAMAPK1MAPTKDM4E
SCHEMBL14345644 0.77 GAA (0.50) GAAALDH1A1LMNANCOA3MAPK1
SCHEMBL12403297 0.77 MAPK1 (0.52) GAAALDH1A1LMNANCOA3MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1737899-B1 DENDRITIC POLYMERS WITH ENHANCED AMPLIFICATION AND INTERIOR FUNCTIONALITY DENDRITIC NANOTECHNOLOGIES INC (US) 2015-07-08 — — EP disclosed
US-7985424-B2 Dendritic polymers with enhanced amplification and interior functionality DENDRITIC NANOTECHNOLOGIES INC. (US) 2011-07-26 — — US disclosed
US-7985424-B2 Dendritic polymers with enhanced amplification and interior functionality DENDRITIC NANOTECHNOLOGIES INC. (US) 2011-07-26 — — US disclosed
US-7981444-B2 Dendritic polymers with enhanced amplification and interior functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2011-07-19 — — US disclosed
US-7981444-B2 Dendritic polymers with enhanced amplification and interior functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2011-07-19 — — US disclosed
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-12-27 — — US disclosed
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-12-27 — — US disclosed
US-20070244296-A1 Dendritic Polymers with Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-10-18 — — US disclosed
US-20070244296-A1 Dendritic Polymers with Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality MYD88, TLR3, TMEM97 GAA 2744/4885ALDH1A1 2720/4885LMNA 1465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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