Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31414645 | 0.97 | ALDH1A1 (0.67) | ALDH1A1GAAMAPK1MAPTTSHR | |
| SCHEMBL31414644 | 0.97 | ALDH1A1 (0.67) | ALDH1A1GAAMAPK1MAPTTSHR | |
| SCHEMBL11449950 | 0.85 | ALDH1A1 (0.54) | ALDH1A1GAAMAPK1MAPTTSHR | |
| SCHEMBL6931910 | 0.84 | MAPK1 (0.69) | ALDH1A1GAAMAPK1MAPTTSHR | |
| SCHEMBL11672344 | 0.84 | MAPK1 (0.69) | ALDH1A1GAAMAPK1MAPTTSHR | |
| SCHEMBL12212607 | 0.84 | KDM4E (0.59) | ALDH1A1GAAMAPK1MAPTTSHR | |
| SCHEMBL13952042 | 0.81 | POLB (0.78) | ALDH1A1GAAMAPK1MAPTTSHR | |
| SCHEMBL10760842 | 0.81 | POLB (0.78) | ALDH1A1MAPK1MAPTTSHRPOLB | |
| SCHEMBL12403146 | 0.81 | GAA (0.64) | ALDH1A1GAAMAPK1MAPTTSHR | |
| SCHEMBL1108387 | 0.80 | POLB (0.52) | ALDH1A1GAAMAPK1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200261442-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | VEPACHEDU SREENIVASARAO (US) | 2020-08-20 | — | — | US | disclosed |
| US-20200069674-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | Exciva GmbH (DE) | 2020-03-05 | — | — | US | disclosed |
| EP-1618146-B9 | STABILISER SYSTEM FOR THE STABILISATION OF HALOGENATED POLYMERS | GALATA CHEMICALS GMBH (DE) | 2012-03-21 | — | — | EP | disclosed |
| EP-1618146-B1 | STABILISER SYSTEM FOR THE STABILISATION OF HALOGENATED POLYMERS | GALATA CHEMICALS GMBH (DE) | 2011-08-17 | — | — | EP | disclosed |
| EP-1461375-B1 | PRESTABILIZATION OF HALOGEN-CONTAINING POLYMERS | CHEMTURA VINYL ADDITIVES GMBH (DE) | 2010-01-27 | — | — | EP | disclosed |
| US-7622541-B2 | Polyurethane coating | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2009-11-24 | — | — | US | disclosed |
| US-7622541-B2 | Polyurethane coating | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2009-11-24 | — | — | US | disclosed |
| US-7615604-B2 | Diols formed by ring-opening of epoxies | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2009-11-10 | — | — | US | disclosed |
| US-7615604-B2 | Diols formed by ring-opening of epoxies | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2009-11-10 | — | — | US | disclosed |
| US-7612133-B2 | Prestabilization of halogen-containing polymers | CHEMTURA VINYL ADDITIVES GMBH (DE) | 2009-11-03 | — | — | US | disclosed |
| EP-1618146-A1 | STABILISER SYSTEM FOR THE STABILISATION OF HALOGENATED POLYMERS | Crompton Vinyl Additives GmbH (DE) | 2006-01-25 | — | — | EP | disclosed |
| EP-1583796-A2 | STABILIZER SYSTEM FOR STABILIZING PVC | Crompton Vinyl Additives GmbH (DE) | 2005-10-12 | — | — | EP | disclosed |
| EP-1343838-B1 | STABILIZER SYSTEM FOR STABILIZING POLYMERS THAT CONTAIN HALOGEN | CROMPTON VINYL ADDITIVES GMBH (DE) | 2005-04-06 | — | — | EP | disclosed |
| US-20040259988-A1 | Prestabilization of halogen-containing polymers | CHEMTURA VINYL ADDITIVES GMBH (DE) | 2004-12-23 | — | — | US | disclosed |
| WO-2004096904-A1 | STABILISER SYSTEM FOR THE STABILISATION OF HALOGENATED POLYMERS | CROMPTON VINYL ADDITIVES GMBH (DE) | 2004-11-11 | — | — | WO | disclosed |
| EP-1461375-A1 | PRESTABILIZATION OF HALOGEN-CONTAINING POLYMERS | Crompton Vinyl Additives GmbH (DE) | 2004-09-29 | — | — | EP | disclosed |
| WO-2004065470-A2 | STABILIZER SYSTEM FOR STABILIZING PVC | CROMPTON VINYL ADDITIVES GMBH (DE) | 2004-08-05 | — | — | WO | disclosed |
| US-20040054043-A1 | Stabilizer system for stabilizing polymers that contain halogen | WACHOVIA CAPITAL FINANCE CORPORATION (NEW ENGLAND) | 2004-03-18 | — | — | US | disclosed |
| WO-2003048233-A1 | STABILIZATION OF DISPERSIONS OF HALOGEN-CONTAINING POLYMERS | CROMPTON VINYL ADDITIVES GMBH (DE) | 2003-06-12 | — | — | WO | disclosed |
| WO-2003048232-A1 | PRESTABILIZATION OF HALOGEN-CONTAINING POLYMERS | CROMPTON VINYL ADDITIVES GMBH (DE) | 2003-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200069674-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | HTR2A, HTR2C, CYP3A43 | ALDH1A1 235/4885GAA 561/4885MAPK1 3886/4885 |
| US-20200261442-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | HTR2C, HTR2A, HTR3A | ALDH1A1 501/4885GAA 1104/4885MAPK1 3827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.