Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12403146 | 0.78 | GAA (0.64) | GAANCOA3ALDH1A1LMNAMAPK1 | |
| SCHEMBL31414645 | 0.68 | ALDH1A1 (0.67) | GAANCOA3ALDH1A1LMNAMAPK1 | |
| SCHEMBL31414644 | 0.68 | ALDH1A1 (0.67) | GAANCOA3ALDH1A1LMNAMAPK1 | |
| SCHEMBL24245304 | 0.67 | TDP1 (0.42) | GAAALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL11672344 | 0.66 | MAPK1 (0.69) | GAANCOA3ALDH1A1LMNAMAPK1 | |
| SCHEMBL759782 | 0.65 | ALDH1A1 (0.67) | GAANCOA3ALDH1A1LMNAMAPK1 | |
| SCHEMBL9636165 | 0.65 | ALDH1A1 (0.62) | GAANCOA3ALDH1A1LMNAMAPK1 | |
| SCHEMBL14345644 | 0.65 | GAA (0.50) | GAANCOA3ALDH1A1LMNAMAPK1 | |
| SCHEMBL6018530 | 0.64 | MAPK1 (0.55) | GAANCOA3ALDH1A1LMNAMAPK1 | |
| SCHEMBL12403297 | 0.62 | MAPK1 (0.52) | GAANCOA3ALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2325236-A1 | Dendritic polymers with enhanced amplification and interior functionality | Dendritic Nanotechnologies Inc. (US) | 2011-05-25 | — | — | EP | disclosed |