Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 3/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5181795 | 0.83 | NPC1 (0.50) | SIGMAR1HTTRAB9ANPC1MMP13 | |
| SCHEMBL22254880 | 0.81 | SIGMAR1 (0.54) | SIGMAR1HTTRAB9ANPC1ACACB | |
| SCHEMBL23481849 | 0.81 | SIGMAR1 (0.87) | SIGMAR1SLC6A4HTR2A | |
| SCHEMBL22255184 | 0.80 | SIGMAR1 (0.53) | SIGMAR1HTTACACBSMN1; SMN2SLC6A4 | |
| SCHEMBL22255188 | 0.80 | SIGMAR1 (0.53) | SIGMAR1HTTACACBSMN1; SMN2SLC6A4 | |
| SCHEMBL25531118 | 0.79 | SIGMAR1 (0.59) | SIGMAR1HTTACACBSLC6A4 | |
| SCHEMBL12404706 | 0.76 | SLC6A4 (0.59) | SIGMAR1HTTRAB9ANPC1ACACB | |
| SCHEMBL18088394 | 0.73 | RAB9A (0.60) | RAB9ANPC1MMP13HPGDSMN1; SMN2 | |
| SCHEMBL13792281 | 0.73 | RAB9A (0.56) | RAB9ANPC1MMP13HPGDSMN1; SMN2 | |
| SCHEMBL13995851 | 0.72 | HTT (0.45) | SIGMAR1HTTHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985882-B1 | Compositions for reductive aminations utilizing supported tricarboxyborohydride reagents and methods of using the same | BIOTAGE AB (SE) | 2011-07-26 | — | — | US | disclosed |