SCHEMBL1240702

SCHEMBL1240702

CCCCCCCCCCCCCCCCC/C=C/C=C/[C]=O

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.55
ALDH1A1 P00352 1/20 0.55
FASN P49327 1/20 0.53
FAAH O00519 7/20 0.48
TRPV1 Q8NER1 1/20 0.48
KDM4E B2RXH2 1/20 0.45
CNR1 P21554 2/20 0.42
CNR2 P34972 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19019742 1.00 TSHR (0.55) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL9696124 1.00 TSHR (0.55) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL9696451 1.00 TSHR (0.55) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL19019745 1.00 TSHR (0.55) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL19019743 1.00 TSHR (0.55) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL9357983 1.00 TSHR (0.55) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL9697099 1.00 TSHR (0.55) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL3122524 1.00 TSHR (0.55) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL9696159 1.00 TSHR (0.55) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL19019770 1.00 TSHR (0.55) TSHRALDH1A1FASNFAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020048596-A1 PREPARATION FOR THE TRANSPORT OF AN ACTIVE SUBSTANCE ACROSS BARRIERS IDEA AG (DE) 2002-04-25 US claimed
EP-4368657-A1 PH-RESPONSIVE LIPID DERIVATIVE NOF Corporation (JP) 2024-05-15 EP disclosed
US-20240099976-A1 BLENDED FORMULATIONS SEQUESSOME TECHNOLOGY HOLDINGS LIMITED (MT) 2024-03-28 US disclosed
US-20240009092-A1 COSMETIC COMPOSITION AND COSMETIC QUASI-DRUG INCLUDING LIPID PARTICLES CONTAINING PHOSPHOLIPID NIPPON SHOKUBAI CO., LTD. (JP) 2024-01-11 US disclosed
WO-2023282296-A1 PH-RESPONSIVE LIPID DERIVATIVE 日油株式会社 2023-01-12 WO disclosed
US-11547665-B2 Multiphasic compositions SEQUESSOME TECHNOLOGY HOLDINGS LIMITED (MT) 2023-01-10 US disclosed
EP-4021643-A1 A COLLECTOR COMPOSITION FOR THE LITHIUM ORE OR MAGNESIUM ORE FLOTATION BASF SE (DE) 2022-07-06 EP disclosed
EP-3954361-A1 MULTIPHASIC COMPOSITIONS Sequessome Technology Holdings Limited (MT) 2022-02-16 EP disclosed
US-20210393655-A1 Vesicular Formulations for Use in the Treatment of Pain or Reduced Mobility of a Joint SEQUESSOME TECHNOLOGY HOLDINGS LIMITED (MT) 2021-12-23 US disclosed
EP-3316857-B1 MULTIPHASIC COMPOSITIONS SEQUESSOME TECH HOLDINGS LIMITED (MT) 2021-08-04 EP disclosed
WO-2010090654-A1 METHODS OF REDUCING THE PROLIFERATION AND VIABILITY OF MICROBIAL AGENTS TDT, LTD. (MT) 2010-08-12 WO disclosed
US-20100197621-A1 METHODS OF REDUCING THE PROLIFERATION AND VIABILITY OF MICROBIAL AGENTS TARGETED DELIVERY TECHNOLOGIES LIMITED (MT) 2010-08-05 US disclosed
US-20100104633-A1 antifungal formulations comprising terbinafine or a pharmaceutically acceptable salt thereof, a lipid, and a surfactant; uses thereof for the treatment of skin and nail fungal infections CEVC GREGOR 2010-04-29 US disclosed
US-20100086504-A1 METHODS OF ADMINISTERING TOPICAL ANTIFUNGAL FORMULATIONS FOR THE TREATMENT OF FUNGAL INFECTIONS TDT LIMITED (MT) 2010-04-08 US disclosed
WO-2010010470-A2 METHODS OF ADMINISTERING TOPICAL ANTIFUNGAL FORMULATIONS FOR THE TREATMENT OF FUNGAL INFECTIONS TDT, LTD (MT) 2010-01-28 WO disclosed
US-20020048596-A1 PREPARATION FOR THE TRANSPORT OF AN ACTIVE SUBSTANCE ACROSS BARRIERS IDEA AG (DE) 2002-04-25 US disclosed
EP-0708645-A1 USE OF COMPOUNDS WHICH INHIBIT PHOSPHATIDIC ACID FORMATION FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF CANCER CELL THERAPEUTICS, INC. (US) 1996-05-01 EP disclosed
WO-1995024199-A2 USE OF COMPOUNDS WHICH INHIBIT PHOSPHATIDIC ACID FORMATION FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF CANCER CELL THERAPEUTICS, INC. (US) 1995-09-14 WO disclosed
EP-0503508-A1 Vesicles and polymeric vesicles Kao Corporation (JP) 1992-09-16 EP disclosed
EP-0036426-B1 NOVEL PROCESS AND INTERMEDIATES USEFUL IN THE PREPARATION OF SYMPATHOMIMETIC AMINES INTERx RESEARCH CORPORATION (US) 1986-04-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240009092-A1 COSMETIC COMPOSITION AND COSMETIC QUASI-DRUG INCLUDING LIPID PARTICLES CONTAINING PHOSPHOLIPID PLIN5, PHOSPHO1, PLIN3 TSHR 1575/4885ALDH1A1 524/4885FASN 174/4885
US-20100104633-A1 antifungal formulations comprising terbinafine or a pharmaceutically acceptable salt thereof, a lipid, and a surfactant; uses thereof for the treatment of skin and nail fungal infections DPM1, PIK3C3, NACA TSHR 3481/4885ALDH1A1 3968/4885FASN 689/4885
US-20100086504-A1 METHODS OF ADMINISTERING TOPICAL ANTIFUNGAL FORMULATIONS FOR THE TREATMENT OF FUNGAL INFECTIONS DPM1, ERG28, NACA TSHR 3546/4885ALDH1A1 3533/4885FASN 289/4885
US-20100197621-A1 METHODS OF REDUCING THE PROLIFERATION AND VIABILITY OF MICROBIAL AGENTS MGLL, LIPA, LPO TSHR 4213/4885ALDH1A1 2166/4885FASN 30/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.