SCHEMBL12410552

SCHEMBL12410552

CSc1ccc(SC)c(F)c1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.35
ALDH1A1 P00352 2/20 0.33
MAP2K2 P36507 1/20 0.33
MAP2K1 Q02750 1/20 0.33
CCR2 P41597 1/20 0.33
HTR7 P34969 1/20 0.33
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
SLC6A4 P31645 1/20 0.32
AR P10275 1/20 0.32
AKR1C3 P42330 3/20 0.32
AKR1C2 P52895 3/20 0.32
NOX1 Q9Y5S8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12410571 0.81 MCL1 (0.35) MCL1ALDH1A1CCR2HTR7KDM4E
SCHEMBL645965 0.80 ALDH1A1 (0.38) MCL1ALDH1A1MAP2K2MAP2K1HTR7
SCHEMBL29722916 0.78 ALDH1A1 (0.42) ALDH1A1
SCHEMBL319042 0.78 ALDH1A1 (0.42) ALDH1A1
SCHEMBL29144903 0.77 MCL1 (0.39) MCL1ALDH1A1KDM4EGAAMAPT
SCHEMBL4417489 0.76 MAPT (0.40) MCL1ALDH1A1MAP2K2MAP2K1HTR7
SCHEMBL12311737 0.76 ALOX15 (0.41) ALDH1A1CCR2GAAMAPTHPGD
SCHEMBL15315300 0.74 MCL1 (0.34) MCL1ALDH1A1MAP2K2MAP2K1HTR7
SCHEMBL12326407 0.74 CCR2 (0.35) CCR2SLC6A4AR
SCHEMBL387740 0.74 KDM1A (0.37) MCL1ALDH1A1MAP2K2MAP2K1HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2334661-B1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS UBE INDUSTRIES (JP) 2017-08-30 EP disclosed
US-8653302-B2 Processes for preparing poly(pentafluorosulfanyl)aromatic compounds UBE INDUSTRIES, LTD. (JP) 2014-02-18 US disclosed
US-8653302-B2 Processes for preparing poly(pentafluorosulfanyl)aromatic compounds UBE INDUSTRIES, LTD. (JP) 2014-02-18 US disclosed
US-20110166392-A1 Processes for Preparing Poly(Pentafluorosulfanyl)Aromatic Compounds UBE INDUSTRIES, LTD. (JP) 2011-07-07 US disclosed
US-20110166392-A1 Processes for Preparing Poly(Pentafluorosulfanyl)Aromatic Compounds UBE INDUSTRIES, LTD. (JP) 2011-07-07 US disclosed
WO-2010033930-A1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS IM&T RESEARCH, INC. (US) 2010-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166392-A1 Processes for Preparing Poly(Pentafluorosulfanyl)Aromatic Compounds PFAS, PUF60, FES MCL1 2531/4885ALDH1A1 4300/4885MAP2K2 1625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.