Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30554004 | 0.88 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10OPRD1 | |
| SCHEMBL30554020 | 0.88 | FPR2 (0.48) | KDM4EALDH1A1HPGDHSD17B10FPR2 | |
| SCHEMBL30554016 | 0.86 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDHSD17B10OPRD1 | |
| SCHEMBL18083960 | 0.86 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDHSD17B10FPR2 | |
| SCHEMBL28714507 | 0.82 | GABRA1 (0.58) | KDM4EALDH1A1HPGDHSD17B10OPRD1 | |
| SCHEMBL12410983 | 0.81 | JMJD6 (0.35) | KDM4EALDH1A1MAPK1JMJD6LMNA | |
| SCHEMBL24070239 | 0.80 | TDP1 (0.46) | ALDH1A1HPGDMAPK1JMJD6CYP3A4 | |
| SCHEMBL30554029 | 0.78 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDHSD17B10FPR2 | |
| SCHEMBL15357759 | 0.78 | SMN1; SMN2 (0.34) | OPRD1OPRK1FPR2SMN1; SMN2ADORA3 | |
| SCHEMBL1822302 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10JMJD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111187218-B | Application of 1-substituted-1H-imidazole-2-carboxylic acid compound in preparation of metal beta-lactamase inhibitor | 四川大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-111253317-B | 1-substituted-1H-imidazole-2-carboxylic acid compound | 四川大学 | 2023-08-04 | — | — | CN | disclosed |
| US-20130289013-A1 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS | SUNOVION PHARMACEUTICALS INC. | 2013-10-31 | — | — | US | disclosed |
| US-20110166146-A1 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS | SUNOVION PHARMACEUTICALS INC. (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166146-A1 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS | PAICS, ITPA, DPYD | KDM4E 3088/4885ALDH1A1 269/4885HPGD 299/4885 |
| US-20130289013-A1 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS | PAICS, ITPA, DPYD | KDM4E 3088/4885ALDH1A1 269/4885HPGD 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.