Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20414287 | 0.84 | FAAH (0.44) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL20414319 | 0.76 | FAAH (0.40) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL20414290 | 0.76 | FAAH (0.40) | TP53FAAHPHGDHMGLLCA12 | |
| SCHEMBL3399855 | 0.74 | TP53 (0.65) | TP53LMNAALDH1A1TSHRGLA | |
| SCHEMBL12411240 | 0.73 | FAAH (0.41) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL24426151 | 0.70 | TP53 (0.39) | TP53FAAHPHGDHMGLLCA12 | |
| SCHEMBL11145953 | 0.70 | FAAH (0.50) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL12411239 | 0.69 | KMT2A (0.51) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL20414312 | 0.69 | KMT2A (0.51) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL22665374 | 0.69 | ALDH1A1 (0.50) | TP53L3MBTL1ALDH1A1TSHRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580990-B2 | Gold catalyzed hydroamination of alkynes and allenes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-11-12 | — | — | US | disclosed |
| US-20110166349-A1 | GOLD CATALYZED HYDROAMINATION OF ALKYNES AND ALLENES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166349-A1 | GOLD CATALYZED HYDROAMINATION OF ALKYNES AND ALLENES | AOC3, AOC2, AOC1 | TP53 2478/4885FAAH 856/4885PHGDH 2019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.