Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 8/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12413879 | 0.89 | PTGES (0.46) | PTGESBRAFGAACYP2D6MET | |
| SCHEMBL12413884 | 0.88 | PTGES (0.42) | PTGESMAPTSMN1; SMN2BRAFGAA | |
| SCHEMBL12377297 | 0.87 | HSD17B10 (0.43) | MAPTNPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL12412020 | 0.84 | NPC1 (0.48) | MAPTNPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL12413883 | 0.81 | HDAC6 (0.49) | NPC1RAB9ABRAFGAAABCG2 | |
| SCHEMBL12413900 | 0.79 | NPC1 (0.49) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL12413913 | 0.76 | SLC1A3 (0.39) | PTGESGAACYP2D6 | |
| SCHEMBL12377283 | 0.75 | MAPT (0.42) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL12377296 | 0.75 | EGFR (0.48) | PTGESMAPTBRAF | |
| SCHEMBL12377281 | 0.74 | P2RX3 (0.44) | MAPTSMN1; SMN2BRAFTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989422-B2 | Antibacterial agents | ALCHEMIA LIMITED (AU) | 2011-08-02 | — | — | US | disclosed |
| US-20090023669-A1 | Antibacterial Agents | ALCHEMIA LIMITED (AU) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023669-A1 | Antibacterial Agents | MRPL21, FUT6, FUT5 | PTGES 1486/4885MAPT 4853/4885NPC1 1617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.