Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23022394 | 0.83 | MAPK1 (0.47) | ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL13360504 | 0.78 | POLB (0.44) | ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL13360488 | 0.75 | POLB (0.48) | ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL6493190 | 0.74 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL2616364 | 0.74 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL5623016 | 0.74 | DRD2 (0.48) | ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL19006734 | 0.73 | POLB (0.52) | ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL10239182 | 0.73 | POLB (0.52) | ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL11193250 | 0.73 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL460865 | 0.72 | DRD2 (0.49) | ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166156-A1 | Prodrugs for the Treatment of Schizophrenia and Bipolar Disease | ALKERMES, INC. (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166156-A1 | Prodrugs for the Treatment of Schizophrenia and Bipolar Disease | SLC1A2, BDNF, MAOB | ALDH1A1 307/4885SMN1; SMN2 1614/4885MAPK1 2549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.