Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1269439 | 0.97 | KDM4E (0.54) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Hydrochloric Acid SCHEMBL425185 | 0.95 | KDM4E (0.58) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Hydrochloric Acid SCHEMBL636765 | 0.95 | KDM4E (0.58) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Water SCHEMBL8528285 | 0.95 | KDM4E (0.52) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Bromide SCHEMBL5088423 | 0.95 | KDM4E (0.52) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Hydrochloric Acid SCHEMBL7263491 | 0.95 | KDM4E (0.58) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Hydrochloric Acid SCHEMBL80718 | 0.95 | KDM4E (0.58) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Iodide SCHEMBL5093184 | 0.95 | KDM4E (0.52) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Iodide SCHEMBL16961611 | 0.93 | KDM4E (0.56) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Ammonia Solution, Strong SCHEMBL10810468 | 0.93 | KDM4E (0.56) | KDM4EALDH1A1TDP1CYP1A2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250381550-A1 | CARBON DISULFIDE TREATED MATERIALS AND METHODS OF PURIFYING FLUIDS USING THE SAME | ZENITH PURIFICATION LLC (US) | 2025-12-18 | — | — | US | claimed |
| WO-2024010846-A2 | CARBON DISULFIDE TREATED MATERIALS AND METHODS OF PURIFYING FLUIDS USING THE SAME | ZENITH PURIFICATION, LLC (US) | 2024-01-11 | — | — | WO | claimed |
| US-9290520-B2 | Cyclic diol-derived blocked mercaptofunctional silane compositions | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2016-03-22 | — | — | US | claimed |
| US-20140076202-A1 | CYCLIC DIOL-DERIVED BLOCKED MERCAPTOFUNCTIONAL SILANE COMPOSITIONS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2014-03-20 | — | — | US | claimed |
| US-8008524-B2 | Process for the preparation of thiocarboxylate silane | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-08-30 | — | — | US | claimed |
| US-8008520-B2 | Process for the preparation of thiocarboxylate silane | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-08-30 | — | — | US | claimed |
| US-20110046264-A1 | CYCLIC DIOL-DERIVED BLOCKED MERCAPTOFUNCTIONAL SILANE COMPOSITIONS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-02-24 | — | — | US | claimed |
| US-20090036701-A1 | Process for the preparation of thiocarboxylate silane | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-02-05 | — | — | US | claimed |
| EP-1831232-A2 | CYCLIC DIOL-DERIVED BLOCKED MERCAPTOFUNCTIONAL SILANE COMPOSITIONS | General Electric Company (US) | 2007-09-12 | — | — | EP | claimed |
| WO-2006023815-A2 | CYCLIC DIOL-DERIVED BLOCKED MERCAPTOFUNCTIONAL SILANE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 2006-03-02 | — | — | WO | claimed |
| WO-2006023785-A2 | CYCLIC DIOL-DERIVED BLOCKED MERCAPTOFUNCTIONAL SILANE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 2006-03-02 | — | — | WO | claimed |
| US-20060041063-A1 | Cyclic diol-derived blocked mercaptofunctional silane compositions | MOMENTIVE PERFORMANCE MATERIALS INC. | 2006-02-23 | — | — | US | claimed |
| US-20050277781-A1 | Process for the preparation of thiocarboxylate silane | MOMENTIVE PERFORMANCE MATERIALS INC. | 2005-12-15 | — | — | US | claimed |
| US-20050245753-A1 | Cyclic diol-derived blocked mercaptofunctional silane compositions | MOMENTIVE PERFORMANCE MATERIALS INC. | 2005-11-03 | — | — | US | claimed |
| US-5093497-A | PROCESS FOR THE PREPARATION OF A SUBSTITUTED OR UNSUBSTITUTED QUINACRIDONE | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | claimed |
| EP-0346765-A2 | Process for preparing 1-(p-tert-butylphenyl)-4-[4'-(alpha-hydroxy-diphenylmethyl)-1'-piperidinyl]butanol | GRUPPO LEPETIT S.p.A. (IT) | 1989-12-20 | — | — | EP | claimed |
| EP-0029409-B1 | PROCESS FOR PREPARING 5-CYANO-5H-DIBENZ(B,F)AZEPINE AND 5H-DIBENZ(B,F)AZEPINE-5-CARBOXAMIDE | CIBA-GEIGY AG (CH) | 1984-08-15 | — | — | EP | claimed |
| US-4436660-A | Process for the production of 5-cyano-and 5-carboxamido-5H-dibenz[b,f]azepines | CIBA-GEIGY CORPORATION (US) | 1984-03-13 | — | — | US | claimed |
| US-20250381550-A1 | CARBON DISULFIDE TREATED MATERIALS AND METHODS OF PURIFYING FLUIDS USING THE SAME | ZENITH PURIFICATION LLC (US) | 2025-12-18 | — | — | US | disclosed |
| US-4081458-A | NON-STEROIDAL BENZOPYRANOXANTHENONES | ELI LILLY AND COMPANY (US) | 1978-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046264-A1 | CYCLIC DIOL-DERIVED BLOCKED MERCAPTOFUNCTIONAL SILANE COMPOSITIONS | TMT1A, SRMS, OR51E2 | ACHE 1134/4885KDM4E 1302/4885ALDH1A1 250/4885 |
| US-20140076202-A1 | CYCLIC DIOL-DERIVED BLOCKED MERCAPTOFUNCTIONAL SILANE COMPOSITIONS | TMT1A, SRMS, OR51E2 | ACHE 1134/4885KDM4E 1302/4885ALDH1A1 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.