Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5292220 | 0.97 | KDM4E (0.54) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Hydrochloric Acid SCHEMBL425185 | 0.95 | KDM4E (0.58) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Iodide SCHEMBL5087561 | 0.95 | KDM4E (0.52) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Hydrochloric Acid SCHEMBL1241484 | 0.95 | KDM4E (0.58) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Water SCHEMBL11057284 | 0.95 | KDM4E (0.52) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Hydrochloric Acid SCHEMBL7263491 | 0.95 | KDM4E (0.58) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Hydrochloric Acid SCHEMBL80718 | 0.95 | KDM4E (0.58) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Bromide SCHEMBL637808 | 0.95 | KDM4E (0.52) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Hydrochloric Acid SCHEMBL7263493 | 0.93 | KDM4E (0.56) | KDM4EALDH1A1TDP1CYP1A2TP53 | |
| Hydrochloric Acid SCHEMBL9653571 | 0.93 | KDM4E (0.56) | KDM4EALDH1A1TDP1CYP1A2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924532-A | Method for extracting polysaccharide from acanthopanax leaves by deep eutectic aqueous two-phase system | 东北农业大学 | 2024-04-26 | — | — | CN | claimed |
| US-6727359-B2 | REACTING PHENOXIDE SULFONYLCHLORIDE AND ACETOACETAMIDE-N-SULFONYL PHENOXIDE AND AMMONIA USING CATALYST | BDL CORPORATION | 2004-04-27 | — | — | US | claimed |
| US-20030065172-A1 | Composition comprising 6-methyl-3,4dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide, its salts, preparation thereof and uses therefor | BDL CORPORATION | 2003-04-03 | — | — | US | claimed |
| EP-0719572-B1 | A process to remove polychloro-bi-phenyls from mineral oils | ENEL SPA (IT) | 1999-07-28 | — | — | EP | claimed |
| EP-0719572-A1 | A process to remove polychloro-bi-phenyls from mineral oils | ENEL S.p.A. (IT) | 1996-07-03 | — | — | EP | claimed |
| CN-117924532-A | Method for extracting polysaccharide from acanthopanax leaves by deep eutectic aqueous two-phase system | 东北农业大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-117924532-A | Method for extracting polysaccharide from acanthopanax leaves by deep eutectic aqueous two-phase system | 东北农业大学 | 2024-04-26 | — | — | CN | disclosed |
| US-8642718-B2 | Curable composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2014-02-04 | — | — | US | disclosed |
| EP-1882713-B1 | CURABLE COMPOSITION | MITSUBISHI GAS CHEMICAL CO (JP) | 2013-07-03 | — | — | EP | disclosed |
| US-8394920-B2 | Composition for resin and optical lens obtained therefrom | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2013-03-12 | — | — | US | disclosed |
| CN-101932630-B | Composition for resin and optical lens obtained therefrom | MITSUBISHI GAS CHEMICAL CO | 2012-12-05 | — | — | CN | disclosed |
| EP-1775315-B1 | POLYMERIZABLE COMPOSITION | MITSUBISHI GAS CHEMICAL CO (JP) | 2012-02-22 | — | — | EP | disclosed |
| US-20040024165-A1 | Composition for optical material | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 2004-02-05 | — | — | US | disclosed |
| EP-1326095-A1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2003-07-09 | — | — | EP | disclosed |
| EP-1319966-A1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2003-06-18 | — | — | EP | disclosed |
| EP-1316819-A1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-20030065172-A1 | Composition comprising 6-methyl-3,4dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide, its salts, preparation thereof and uses therefor | BDL CORPORATION | 2003-04-03 | — | — | US | disclosed |
| US-4082627-A | ELECTROLYTIC REDUCTION OF DIHYDROBENZOPYRANOXANTHENONES | ELI LILLY AND COMPANY (US) | 1978-04-04 | — | — | US | disclosed |
| US-4081458-A | NON-STEROIDAL BENZOPYRANOXANTHENONES | ELI LILLY AND COMPANY (US) | 1978-03-28 | — | — | US | disclosed |
| US-3945794-A | Production of level dyeings on acrylonitrile polymer fibers with basic dyes | BASF AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065172-A1 | Composition comprising 6-methyl-3,4dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide, its salts, preparation thereof and uses therefor | PDXK, ITK, KHK | ACHE 1824/4885KDM4E 98/4885ALDH1A1 636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.