Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2695113 | 0.81 | CYP1A2 (0.33) | MAPT | |
| SCHEMBL12416124 | 0.80 | P2RX3 (0.36) | — | |
| SCHEMBL12416129 | 0.79 | ADORA3 (0.36) | MAPT | |
| SCHEMBL14702196 | 0.75 | ABL1 (0.32) | — | |
| SCHEMBL26455116 | 0.73 | POLB (0.36) | — | |
| SCHEMBL26455085 | 0.73 | POLB (0.36) | — | |
| SCHEMBL18708173 | 0.73 | ABL1 (0.32) | — | |
| SCHEMBL18503734 | 0.73 | ABL1 (0.32) | — | |
| SCHEMBL17414088 | 0.70 | ABL1 (0.32) | — | |
| SCHEMBL2694973 | 0.70 | POLB (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140073786-A1 | CYCLOHEXENYL NUCLEIC ACIDS ANALOGS | ISIS PHARMACEUTICALS, INC. (US) | 2014-03-13 | — | — | US | disclosed |
| US-20110172294-A1 | CYCLOHEXENYL NUCLEIC ACIDS ANALOGS | IONIS PHARMACEUTICALS, INC. | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172294-A1 | CYCLOHEXENYL NUCLEIC ACIDS ANALOGS | POLM, POLRMT, HNRNPM | MAPT 4038/4885ALOX15 2479/4885KMT2A 2175/4885 |
| US-20140073786-A1 | CYCLOHEXENYL NUCLEIC ACIDS ANALOGS | POLM, POLRMT, HNRNPM | MAPT 4113/4885ALOX15 3135/4885KMT2A 1974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.