SCHEMBL124165

SCHEMBL124165

CC(=O)OCC(=O)[C@@]12OC(C)(C)O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)C3(F)[C@@H](O)C[C@@]12C

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 9/20 0.87
▸ LMNA P02545 8/20 0.87
▸ CYP3A4 P08684 6/20 0.87
▸ NR3C1 P04150 5/20 0.87
▸ PGR P06401 4/20 0.87
▸ CNR1 P21554 2/20 0.87
▸ NPSR1 Q6W5P4 2/20 0.87
▸ MAPT P10636 2/20 0.87
▸ KCNH2 Q12809 1/20 0.87
▸ USP2 O75604 1/20 0.87
▸ NR1I2 O75469 1/20 0.81
▸ ALDH1A1 P00352 2/20 0.75
▸ AR P10275 2/20 0.75
▸ MEN1 O00255 1/20 0.75
▸ KMT2A Q03164 1/20 0.75
▸ CYP2C9 P11712 1/20 0.69
▸ TBXA2R P21731 1/20 0.69
▸ SMN1; SMN2 Q16637 1/20 0.69
▸ HSD17B10 Q99714 1/20 0.60
▸ TDP1 Q9NUW8 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14884636 1.00 HIF1A (0.87) HIF1ALMNACYP3A4NR3C1PGR
SCHEMBL28971361 1.00 HIF1A (0.87) HIF1ALMNACYP3A4NR3C1PGR
SCHEMBL11422147 1.00 HIF1A (0.87) HIF1ALMNACYP3A4NR3C1PGR
SCHEMBL15975096 1.00 HIF1A (0.87) HIF1ALMNACYP3A4NR3C1PGR
SCHEMBL1973547 0.94 HIF1A (0.81) HIF1ALMNACYP3A4NR3C1PGR
Amcinonide SCHEMBL13026154 0.93 HIF1A (1.00) HIF1ALMNACYP3A4NR3C1PGR
Amcinonide SCHEMBL5488922 0.93 HIF1A (1.00) HIF1ALMNACYP3A4NR3C1PGR
Amcinonide SCHEMBL4720 0.93 HIF1A (1.00) HIF1ALMNACYP3A4NR3C1PGR
Amcinonide SCHEMBL21051752 0.93 HIF1A (1.00) HIF1ALMNACYP3A4NR3C1PGR
Amcinonide SCHEMBL1649481 0.93 HIF1A (1.00) HIF1ALMNACYP3A4NR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1520 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4504786-A1 ENGINEERED CD200R ANTIBODIES AND USES THEREOF MiroBio Limited (GB) 2025-02-12 — — EP claimed
CN-118141762-B Foam-type pharmaceutical agent and foam composition for topical application 北京罗诺强施医药技术研发中心有限公司 2024-07-12 — — CN claimed
WO-2024067327-A1 USE OF TRITERPENOID SAPONIN COMPOUND IN PREPARATION OF MEDICAMENT FOR PREVENTING AND/OR TREATING NODULE, FIBROSIS, OR GRANULOMA DISEASES 浙江普利药业有限公司 2024-04-04 — — WO claimed
US-20230416361-A1 ENGINEERED CD200R ANTIBODIES AND USES THEREOF OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2023-12-28 — — US claimed
WO-2023196866-A1 ENGINEERED CD200R ANTIBODIES AND USES THEREOF MIROBIO LIMITED (GB) 2023-10-12 — — WO claimed
CN-116406296-A Treatment of lupus attacks 阿斯利康(瑞典)有限公司 2023-07-07 — — CN claimed
US-20210315842-A1 STABLE PHARMACEUTICAL COMPOSITIONS FOR PRESSURIZED METERED DOSE INHALERS LUPIN INC (US) 2021-10-14 — — US claimed
CN-112702993-A Pharmaceutical compositions suitable for joint delivery and their use in the treatment of joint pain TLC生物医药公司 2021-04-23 — — CN claimed
EP-3801457-A1 STABLE PHARMACEUTICAL COMPOSITIONS FOR PRESSURIZED METERED DOSE INHALERS Lupin Inc. (US) 2021-04-14 — — EP claimed
US-20210000758-A1 TREATMENT OF OCULAR DISEASES WITH OPHTHALMIC TAPINAROF COMPOSITIONS SOL-GEL TECHNOLOGIES LTD. (IL) 2021-01-07 — — US claimed
EP-1180020-A2 POROUS DRUG MATRICES AND METHODS OF MANUFACTURE THEREOF Acusphere, Inc. (US) 2002-02-20 — — EP claimed
US-20020013320-A1 Use of growth hormone secretagogues to treat systemic lupus erythematosus and inflammatory bowel disease BUSCH FRANK ROBERT (US) 2002-01-31 — — US claimed
WO-2000072827-A9 POROUS DRUG MATRICES AND METHODS OF MANUFACTURE THEREOF ACUSPHERE INC (US) 2002-01-31 — — WO claimed
EP-1166778-A2 The use of growth hormone scretagogues to treat systemic lupus erythematosus and inflammatory bowel disease Pfizer Products Inc. (US) 2002-01-02 — — EP claimed
US-6203813-B1 OPIATE ANTAGONIST, STEROIDAL ANTIINFLAMMATORY AGENT AND CARRIER; SUSTAINED RELEASE; DRUG ABUSE TREATMENT GOOBERMAN, LANCE L. 2001-03-20 — — US claimed
WO-2000072827-A2 POROUS DRUG MATRICES AND METHODS OF MANUFACTURE THEREOF ACUSPHERE, INC. (US) 2000-12-07 — — WO claimed
WO-2000057845-A1 METHOD FOR REMOVAL OF HUMAN HORNY TISSUES JOHNSON AND JOHNSON CONSUMER COMPANIES, INC. (US) 2000-10-05 — — WO claimed
CN-1239656-A Compound transdermal nicotine-clonidine paster for giving up smoking UNIV CHONGQING MEDICAL (CN) 1999-12-29 — — CN claimed
US-4944939-A Mixture of salicylic acid, glucocorticoid, and sulfur MOORE MILTON D (US) 1990-07-31 — — US claimed
US-4478818-A Ocular preparation housing steroid in two different therapeutic forms ALZA CORPORATION (US) 1984-10-23 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020013320-A1 Use of growth hormone secretagogues to treat systemic lupus erythematosus and inflammatory bowel disease GHSR, GHRHR, CRH HIF1A 1681/4885LMNA 2598/4885CYP3A4 3427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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