Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.87 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.87 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12417294 | 0.94 | MAPT (0.76) | MAPTNPSR1KDM4EHTTMAPK1 | |
| SCHEMBL15107850 | 0.93 | MAPT (1.00) | MAPTNPSR1KDM4EHTTMAPK1 | |
| SCHEMBL12417291 | 0.89 | MAPT (0.69) | MAPTNPSR1KDM4EHTTMAPK1 | |
| SCHEMBL13845573 | 0.87 | MAPT (0.88) | MAPTNPSR1KDM4EHTTMAPK1 | |
| SCHEMBL12508077 | 0.82 | MAPT (0.79) | MAPTNPSR1KDM4EHTTMAPK1 | |
| SCHEMBL13845572 | 0.81 | MAPT (0.79) | MAPTNPSR1KDM4EMAPK1LMNA | |
| SCHEMBL12417295 | 0.77 | MAPT (0.76) | MAPTNPSR1KDM4EHTTMAPK1 | |
| SCHEMBL15107847 | 0.70 | MAPT (0.89) | MAPTNPSR1KDM4EMAPK1LMNA | |
| SCHEMBL13234488 | 0.69 | KDM4E (0.71) | MAPTKDM4EHTTLMNANPC1 | |
| SCHEMBL27193044 | 0.67 | RAB9A (0.77) | MAPTKDM4EHTTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8486987-B2 | Mechanism-based small-molecule parasite inhibitors | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2013-07-16 | — | — | US | disclosed |
| US-20110172268-A1 | MECHANISM-BASED SMALL-MOLECULE PARASITE INHIBITORS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172268-A1 | MECHANISM-BASED SMALL-MOLECULE PARASITE INHIBITORS | SERPINB1, TFPI, CYP27A1 | MAPT 4545/4885NPSR1 3883/4885KDM4E 3641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.