Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 5/20 | 0.43 |
| ▸ | NPY1R | P25929 | 5/20 | 0.43 |
| ▸ | NPY2R | P49146 | 4/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | NMT2 | O60551 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 2/20 | 0.37 |
| ▸ | FNTB | P49356 | 2/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13372149 | 0.92 | SIRT5 (0.54) | MEN1KMT2ASIRT5TLR2NPY4R | |
| SCHEMBL12892975 | 0.92 | SIRT5 (0.54) | MEN1KMT2ASIRT5TLR2NPY4R | |
| SCHEMBL17350018 | 0.87 | NPY4R (0.53) | SIRT5TLR2NPY4RNPY1RNPY2R | |
| SCHEMBL17849796 | 0.87 | NPY4R (0.53) | SIRT5TLR2NPY4RNPY1RNPY2R | |
| SCHEMBL13347267 | 0.84 | SIRT5 (0.47) | MEN1KMT2ASIRT5TLR2NPY4R | |
| SCHEMBL24918963 | 0.82 | PTPN1 (0.43) | SIRT5TLR2NPY4RNPY1RNPY2R | |
| SCHEMBL20799366 | 0.81 | NPY4R (0.49) | TLR2NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL17849843 | 0.81 | NPY4R (0.51) | TLR2NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL14601040 | 0.81 | SIRT5 (0.65) | SIRT5TLR2SIRT6SIRT1ALB | |
| SCHEMBL12892988 | 0.81 | SIRT5 (0.55) | MEN1KMT2ASIRT5TLR2NPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450097-B2 | Protein-proteophore complexes | ASCENDIS PHARMA GMBH (DE) | 2013-05-28 | — | — | US | disclosed |
| US-20110172390-A1 | Protein-Proteophore Complexes | ASCENDIS PHARMA A/S (DK) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172390-A1 | Protein-Proteophore Complexes | PSMG3, PSME1, PSMD11 | MEN1 3010/4885KMT2A 2932/4885SIRT5 3870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.