Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 2/20 | 0.38 |
| ▸ | NPY2R | P49146 | 2/20 | 0.38 |
| ▸ | NPY4R | P50391 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | NMT2 | O60551 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 2/20 | 0.35 |
| ▸ | FNTB | P49356 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12892975 | 0.92 | SIRT5 (0.54) | SIRT5SIRT6SIRT1FOLH1KDM4E | |
| SCHEMBL13372149 | 0.92 | SIRT5 (0.54) | SIRT5SIRT6SIRT1FOLH1KDM4E | |
| SCHEMBL13347278 | 0.86 | SIRT6 (0.57) | SIRT5SIRT6SIRT1FOLH1TLR2 | |
| SCHEMBL12417527 | 0.84 | MEN1 (0.45) | SIRT5SIRT6SIRT1TLR2NPY1R | |
| SCHEMBL13371945 | 0.82 | SIRT5 (0.57) | SIRT5SIRT6SIRT1TLR2NPY1R | |
| SCHEMBL13166978 | 0.82 | SIRT6 (0.48) | SIRT5SIRT6SIRT1FOLH1KDM4E | |
| SCHEMBL14601040 | 0.81 | SIRT5 (0.65) | SIRT5SIRT6SIRT1FOLH1KDM4E | |
| SCHEMBL13166855 | 0.78 | SIRT6 (0.45) | SIRT5SIRT6SIRT1FOLH1KDM4E | |
| SCHEMBL13402312 | 0.78 | MEN1 (0.59) | SIRT5SIRT6SIRT1FOLH1MEN1 | |
| SCHEMBL13402412 | 0.78 | KDM4E (0.47) | FOLH1KDM4EMEN1KMT2AFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100111865-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100111865-A1 | CONTRAST AGENTS | CSGALNACT1, HPSE, SERPINC1 | SIRT5 3907/4885SIRT6 4265/4885SIRT1 4221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.