Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.54 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 3/20 | 0.42 |
| ▸ | NPY2R | P49146 | 3/20 | 0.42 |
| ▸ | NPY4R | P50391 | 3/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.38 |
| ▸ | NMT2 | O60551 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12892975 | 1.00 | SIRT5 (0.54) | SIRT5SIRT6SIRT1TLR2NPY1R | |
| SCHEMBL13347267 | 0.92 | SIRT5 (0.47) | SIRT5SIRT6SIRT1TLR2NPY1R | |
| SCHEMBL12417527 | 0.92 | MEN1 (0.45) | SIRT5SIRT6SIRT1TLR2NPY1R | |
| SCHEMBL14601040 | 0.90 | SIRT5 (0.65) | SIRT5SIRT6SIRT1TLR2FOLH1 | |
| SCHEMBL13371945 | 0.88 | SIRT5 (0.57) | SIRT5SIRT6SIRT1TLR2NPY1R | |
| SCHEMBL17350018 | 0.85 | NPY4R (0.53) | SIRT5TLR2NPY1RNPY2RNPY4R | |
| SCHEMBL17849796 | 0.85 | NPY4R (0.53) | SIRT5TLR2NPY1RNPY2RNPY4R | |
| SCHEMBL13347278 | 0.84 | SIRT6 (0.57) | SIRT5SIRT6SIRT1TLR2FOLH1 | |
| SCHEMBL12680278 | 0.82 | SIRT5 (0.49) | SIRT5SIRT6SIRT1TLR2FOLH1 | |
| SCHEMBL12892923 | 0.81 | SIRT5 (0.55) | SIRT5SIRT6SIRT1TLR2NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100111865-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100111865-A1 | CONTRAST AGENTS | CSGALNACT1, HPSE, SERPINC1 | SIRT5 3907/4885SIRT6 4265/4885SIRT1 4221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.