Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | TNF | P01375 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6305900 | 0.83 | MAOA (0.48) | CYP1A2MAOAHPGDNPC1RAB9A | |
| SCHEMBL4758381 | 0.79 | TRPA1 (0.54) | CYP1A2TRPA1MAOANOS3NOS1 | |
| SCHEMBL2369908 | 0.79 | CYP1A2 (0.42) | CYP1A2TRPA1MAOANOS3NOS1 | |
| SCHEMBL56649 | 0.79 | NOS3 (0.52) | CYP1A2TRPA1MAOANOS3NOS1 | |
| SCHEMBL519052 | 0.76 | CYP2A6 (0.45) | CYP1A2MAOANOS3NOS1NOS2 | |
| SCHEMBL207849 | 0.74 | TRPA1 (0.41) | CYP1A2TRPA1MAOANOS3NOS1 | |
| SCHEMBL2138630 | 0.73 | MAOA (0.52) | CYP1A2MAOACYP19A1TNFCES1 | |
| SCHEMBL2095176 | 0.73 | KDM4E (0.39) | MAOACYP2A6HPGDNPC1RAB9A | |
| SCHEMBL8429416 | 0.71 | TRPA1 (0.42) | CYP1A2TRPA1MAOANOS3NOS1 | |
| SCHEMBL2582425 | 0.70 | AHR (0.43) | HPGDAHRPDE3BPDE3AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3089 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3915405-B1 | AEROSOL GENERATION SYSTEM | INNO IT CO LTD (KR) | 2024-09-04 | — | — | EP | claimed |
| WO-2024121013-A1 | SULFONYL DERIVATIVES AS CCR6 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-06-13 | — | — | WO | claimed |
| WO-2024112258-A1 | SEROTONIN RECEPTOR AS A TARGET FOR THERAPY | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2024-05-30 | — | — | WO | claimed |
| WO-2024108155-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2024-05-23 | — | — | WO | claimed |
| US-RE49851-E1 | Pyridinylaminopyrimidine derivatives, preparation process and use thereof | SHANGHAI ALLIST PHARMACEUTICALS CO., LTD. (CN) | 2024-02-27 | — | — | US | claimed |
| WO-2024035950-A1 | INHIBITORS OF KIF18A AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2024-02-15 | — | — | WO | claimed |
| US-11866430-B2 | Naphthyridinone compounds useful as T cell activators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-09 | — | — | US | claimed |
| CN-112585139-B | Naphthyridinone compounds as T cell activators | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | claimed |
| WO-2023225244-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | BIOGEN MA INC. (US) | 2023-11-23 | — | — | WO | claimed |
| US-11744824-B2 | 2-amino-3-carbonyl imidazopyridine and pyrazolopyridine compounds | 1ST Biotherapeutics, Inc. (KR) | 2023-09-05 | — | — | US | claimed |
| EP-0347766-A2 | 4,5,7,8-Tetrahydro-6H-thiazolo[5,4-d]azepines, their preparation and their use as medicaments | Dr. Karl Thomae GmbH (DE) | 1989-12-27 | — | — | EP | claimed |
| EP-0200915-B1 | AMINOPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1989-09-27 | — | — | EP | claimed |
| EP-0280844-A1 | Soap-based cosmetic composition | Singh-Verma, Shyam Bir, Dr. (DE) | 1988-09-07 | — | — | EP | claimed |
| WO-1988005655-A1 | SOAP-BASED COSMETIC FOR THE BODY | EAU DE COLOGNE- & PARFÜMERIE-FABRIK GLOCKENGASSE N (DE) | 1988-08-11 | — | — | WO | claimed |
| EP-0221958-A4 | 3-AMINOPROPYLOXYPHENYL DERIVATIVES THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | LOUIS WILLIAM JOHN (AU) | 1987-11-25 | — | — | EP | claimed |
| EP-0221958-A1 | 3-AMINOPROPYLOXYPHENYL DERIVATIVES THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | LOUIS WILLIAM JOHN (AU) | 1987-05-20 | — | — | EP | claimed |
| WO-1986006717-A1 | 3-AMINOPROPYLOXYPHENYL DERIVATIVES THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LOUIS WILLIAM JOHN (AU) | 1986-11-20 | — | — | WO | claimed |
| US-4581356-A | HYPOTENSIVE AND ANTIULCER AGENTS; ANTICOAGULANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-08 | — | — | US | claimed |
| US-4545806-A | 5-(Oxo or thio heterocycle) cyclohexane-1,3-dione derivatives and their use for controlling undesirable plant growth | BASF AKTIENGESELLSCHAFT (DE) | 1985-10-08 | — | — | US | claimed |
| EP-0122494-A2 | Triazine derivatives, processes for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-24 | — | — | EP | claimed |