Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14566440 | 0.80 | NOS3 (0.50) | CYP1A2MAOANOS3NOS1NOS2 | |
| SCHEMBL124176 | 0.79 | CYP1A2 (0.44) | CYP1A2TRPA1MAOANOS3NOS1 | |
| SCHEMBL599843 | 0.78 | CES1 (0.42) | CYP1A2TRPA1MAOANOS3NOS1 | |
| SCHEMBL7824209 | 0.77 | CYP1A2 (0.48) | CYP1A2TRPA1MAOANOS3NOS1 | |
| Cyclamic Acid SCHEMBL6788056 | 0.75 | HSP90AA1 (0.37) | GAARAB9ASMN1; SMN2 | |
| SCHEMBL6223560 | 0.75 | ALDH1A1 (0.34) | HPGDPKMTLR9NPC1RAB9A | |
| SCHEMBL19134062 | 0.73 | ALDH1A1 (0.42) | HPGDGAA | |
| SCHEMBL5844144 | 0.72 | NOS3 (0.35) | CYP1A2TRPA1MAOANOS3NOS1 | |
| SCHEMBL207849 | 0.72 | TRPA1 (0.41) | CYP1A2TRPA1MAOANOS3NOS1 | |
| SCHEMBL10816499 | 0.71 | CYP1A2 (0.52) | CYP1A2TRPA1MAOANOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025011623-A1 | CYANOQUINOLINE-TARGETING PROTEIN DEGRADATION MOLECULE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海壹迪生物技术有限公司 | 2025-01-16 | — | — | WO | claimed |
| US-20230075693-A1 | FLUORESCENT CURABLE DENTAL COMPOSITION AND CURED PRODUCT THEREOF | KURARAY NORITAKE DENTAL INC. (JP) | 2023-03-09 | — | — | US | claimed |
| EP-4079280-A1 | FLUORESCENT CURABLE DENTAL COMPOSITION AND CURED PRODUCT THEREOF | Kuraray Noritake Dental Inc. (JP) | 2022-10-26 | — | — | EP | claimed |
| EP-2398324-B1 | PYRAZOLO [4,3-c]CINNOLIN-3-ONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME (US) | 2014-09-03 | — | — | EP | claimed |
| EP-2398324-A1 | PYRAZOLO [4,3-c]CINNOLIN-3-ONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | Merck Sharp & Dohme Corp. (US) | 2011-12-28 | — | — | EP | claimed |
| WO-2010096338-A1 | PYRAZOLO [4,3-c] CINNOLIN-3-ONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2010-08-26 | — | — | WO | claimed |
| CN-1218472-A | Pharmaceutically useful compounds | ASTRA PHARMA PROD (GB) | 1999-06-02 | — | — | CN | claimed |
| EP-0187551-A1 | Pyrazolo[4,3-c]cinnolin-3-one derivatives, their salts, preparation process, use as medicaments, compositions containing them and intermediate products | ROUSSEL-UCLAF (FR) | 1986-07-16 | — | — | EP | claimed |
| CN-121513008-A | Pharmaceutical composition of aza-quinolinone derivative, preparation method and application | 成都硕德药业有限公司 | 2026-02-13 | — | — | CN | disclosed |
| US-20250346573-A1 | AZAQUINOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | CHENGDU EASTON BIOPHARMACEUTICALS CO LTD (CN) | 2025-11-13 | — | — | US | disclosed |
| US-20250346573-A1 | AZAQUINOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | CHENGDU EASTON BIOPHARMACEUTICALS CO LTD (CN) | 2025-11-13 | — | — | US | disclosed |
| US-12465559-B2 | Fluorescent curable dental composition and cured product thereof | KURARAY NORITAKE DENTAL INC. (JP) | 2025-11-11 | — | — | US | disclosed |
| EP-4534533-A1 | AZAQUINOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Chengdu Easton Biopharmaceuticals Co., Ltd. (CN) | 2025-04-09 | — | — | EP | disclosed |
| CN-119735558-A | Preparation method and intermediate of aza-quinolinone derivative | 成都苑东生物制药股份有限公司 | 2025-04-01 | — | — | CN | disclosed |
| WO-1987003201-A1 | BENZODIAZINONE-PYRIDAZINONE AND HYDROXY-PYRAZOLYL COMPOUNDS, CARDIOTONIC COMPOSITIONS INCLUDING THE SAME, AND THEIR USES | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1987-06-04 | — | — | WO | disclosed |
| WO-1987003199-A1 | HYDROXY AND AMINOTHIAZOLYL-BENZODIAZINONE COMPOUNDS, CARDIOTONIC COMPOSITIONS INCLUDING THE SAME, AND THEIR USES | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1987-06-04 | — | — | WO | disclosed |
| EP-0197226-A1 | Chemical hybridization agents comprising derivatives of cinnoline-3-carboxylic acids, and their application | LAFARGE COPPEE (FR) | 1986-10-15 | — | — | EP | disclosed |
| EP-0187551-A1 | Pyrazolo[4,3-c]cinnolin-3-one derivatives, their salts, preparation process, use as medicaments, compositions containing them and intermediate products | ROUSSEL-UCLAF (FR) | 1986-07-16 | — | — | EP | disclosed |
| EP-0187551-A1 | Pyrazolo[4,3-c]cinnolin-3-one derivatives, their salts, preparation process, use as medicaments, compositions containing them and intermediate products | ROUSSEL-UCLAF (FR) | 1986-07-16 | — | — | EP | disclosed |
| US-4198235-A | Dye diffusion transfer process employing compounds that release sulfonamide dye providing radicals | AGFA-GEVAERT, A.G. (DE) | 1980-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12465559-B2 | Fluorescent curable dental composition and cured product thereof | BRD1, TBCA, BAZ1A | CYP1A2 3884/4885TRPA1 303/4885MAOA 1620/4885 |
| US-20250346573-A1 | AZAQUINOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | PARP1, PARP8, PARP11 | CYP1A2 516/4885TRPA1 4536/4885MAOA 332/4885 |
| US-20230075693-A1 | FLUORESCENT CURABLE DENTAL COMPOSITION AND CURED PRODUCT THEREOF | BRD1, TBCA, BAZ1A | CYP1A2 3884/4885TRPA1 303/4885MAOA 1620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.