Sugi Predict

Sugi Predict / Compounds / SCHEMBL12419220

SCHEMBL12419220

SCHEMBL12419220

OB(O)c1ccc2nc(Oc3ccccc3)ccc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 2/20 0.51
▸ CA2 P00918 2/20 0.51
▸ ALDH1A1 P00352 2/20 0.43
▸ HPGD P15428 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ HTT P42858 1/20 0.41
▸ MAP4K4 O95819 1/20 0.41
▸ PLA2G10 O15496 3/20 0.39
▸ ENPP2 Q13822 2/20 0.37
▸ TDP1 Q9NUW8 2/20 0.36
▸ MAPK1 P28482 2/20 0.36
▸ L3MBTL1 Q9Y468 3/20 0.36
▸ BCAT2 O15382 1/20 0.36
▸ LMNA P02545 1/20 0.35
▸ MGLL Q99685 1/20 0.35
▸ F2 P00734 1/20 0.35
▸ F10 P00742 1/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12419256 0.89 CA1 (0.51) CA1CA2ALDH1A1HPGDKDM4E
SCHEMBL12419239 0.85 HTT (0.42) CA1CA2ALDH1A1HPGDHTT
SCHEMBL12419222 0.85 ENPP2 (0.53) CA1CA2ALDH1A1KDM4EHSD17B10
SCHEMBL12419251 0.85 MAP4K4 (0.47) CA1CA2ALDH1A1HTTMAP4K4
SCHEMBL12419230 0.85 MAP4K4 (0.49) CA1CA2MAP4K4ENPP2L3MBTL1
SCHEMBL12419224 0.83 CA1 (0.40) CA1CA2MAP4K4ENPP2F2
SCHEMBL12419229 0.82 MAP4K4 (0.52) CA1CA2MAP4K4ENPP2
SCHEMBL12419254 0.81 SCN7A (0.44) CA1CA2KDM4EMAP4K4ENPP2
SCHEMBL12419232 0.81 CA1 (0.44) CA1CA2ALDH1A1HPGDKDM4E
SCHEMBL12419227 0.80 ALDH1A1 (0.47) CA1CA2ALDH1A1KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150368278-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE INFINITY PHARMACEUTICALS, INC. (US) 2015-12-24 — — US disclosed
US-20150368278-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE INFINITY PHARMACEUTICALS, INC. (US) 2015-12-24 — — US disclosed
US-8957049-B2 Inhibitors of fatty acid amide hydrolase INFINITY PHARMACEUTICALS, INC. (US) 2015-02-17 — — US disclosed
US-8957049-B2 Inhibitors of fatty acid amide hydrolase INFINITY PHARMACEUTICALS, INC. (US) 2015-02-17 — — US disclosed
US-20110172186-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE INFINITY PHARMACEUTICALS, INC. 2011-07-14 — — US disclosed
US-20110172186-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE INFINITY PHARMACEUTICALS, INC. 2011-07-14 — — US disclosed
WO-2009126691-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE INFINITY PHARMACEUTICALS, INC (US) 2009-10-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110172186-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE FAAH, FAAH2, ASAH1 CA1 822/4885CA2 1487/4885ALDH1A1 354/4885
US-20150368278-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE FAAH, FAAH2, ASAH1 CA1 822/4885CA2 1487/4885ALDH1A1 354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.