SCHEMBL12419959

SCHEMBL12419959

COC(OC)c1ccc(C(C)(C)O)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 1/20 0.39
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
HIF1A Q16665 1/20 0.34
PDE4A P27815 1/20 0.33
DHODH Q02127 1/20 0.33
TNKS O95271 1/20 0.33
PARP1 P09874 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
HSD11B1 P28845 3/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
KCNH2 Q12809 1/20 0.32
GRIN2B Q13224 2/20 0.31
PDE2A O00408 2/20 0.31
NPSR1 Q6W5P4 2/20 0.30
TSHR P16473 2/20 0.30
LMNA P02545 1/20 0.30
TYR P14679 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL799991 0.82 TSHR (0.44) NPSR1TSHRLMNATYRHPGD
SCHEMBL21300009 0.81 CYP2C9 (0.33) CYP2D6CYP2C9HIF1ACYP3A4
SCHEMBL6680120 0.78 MAPK1 (0.33) HSD11B1PDE2A
SCHEMBL21299993 0.78 PDE2A (0.42) GRIN2BPDE2ATSHR
SCHEMBL8955219 0.78 CA12 (0.35) CYP2D6NPSR1TSHRESR1CYP3A4
SCHEMBL3281443 0.78 NR1H2 (0.50) NPSR1LMNA
SCHEMBL6933846 0.77 OPRD1 (0.43) OPRD1CYP2D6CYP2C9HIF1APDE4A
SCHEMBL9641589 0.76 CYP2D6 (0.42) CYP2D6CYP2C9HIF1APDE4AMEN1
SCHEMBL9454249 0.76 CES2 (0.35) OPRD1GRIN2BESR1ESR2
SCHEMBL11393154 0.76 PDE2A (0.44) PDE2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110207968-A1 PROCESS FOR PREPARING 4-ISOPROPYLCYCLOHEXYLMETHANOL BASF SE (DE) 2011-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110207968-A1 PROCESS FOR PREPARING 4-ISOPROPYLCYCLOHEXYLMETHANOL CYP2E1, CYP3A4, DHPS OPRD1 911/4885CYP2D6 131/4885CYP2C9 41/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.