Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.51 |
| ▸ | KHK | P50053 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14624277 | 0.91 | HRH1 (0.59) | HRH1KHKIKBKBSLC6A2SLC6A4 | |
| SCHEMBL24721545 | 0.90 | HRH1 (0.56) | HRH1KHKIKBKBCHUKSLC6A2 | |
| SCHEMBL21481540 | 0.86 | HRH1 (0.54) | HRH1KHKSLC6A2SLC6A4NMT1 | |
| SCHEMBL18617341 | 0.83 | CHRNB2 (0.51) | HRH1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12420639 | 0.82 | HRH1 (0.71) | HRH1IKBKBCHUKSLC6A2SLC6A4 | |
| SCHEMBL18019002 | 0.80 | ALDH1A1 (0.46) | HRH1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14624276 | 0.80 | HRH1 (0.56) | HRH1IKBKBNMT1 | |
| SCHEMBL13806451 | 0.78 | HRH1 (0.55) | HRH1KHKSLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL2196129 | 0.78 | HRH1 (0.47) | HRH1 | |
| SCHEMBL11941056 | 0.77 | ALDH1A1 (0.49) | HRH1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | FAAH, FAAH2, UTS2R | HRH1 75/4885KHK 1497/4885IKBKB 285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.