Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2196646 | 0.99 | HRH3 (0.50) | HRH3CYP2D6DRD2DRD4SIGMAR1 | |
| SCHEMBL3996239 | 0.82 | FAAH (0.55) | — | |
| SCHEMBL2193581 | 0.81 | FAAH (0.52) | HRH3 | |
| SCHEMBL12420874 | 0.80 | CXCR4 (0.50) | HRH3DRD2DRD4SIGMAR1 | |
| SCHEMBL9734996 | 0.80 | SIGMAR1 (0.51) | DRD2DRD4SIGMAR1 | |
| SCHEMBL12420616 | 0.79 | SIGMAR1 (0.48) | HRH3SIGMAR1 | |
| SCHEMBL9736013 | 0.79 | SIGMAR1 (0.50) | DRD2DRD4SIGMAR1HRH2 | |
| SCHEMBL25120369 | 0.79 | FAAH (0.55) | CYP2D6 | |
| SCHEMBL2194586 | 0.78 | FAAH (0.48) | — | |
| SCHEMBL15012021 | 0.78 | SIGMAR1 (0.51) | DRD2DRD4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | FAAH, FAAH2, UTS2R | HRH3 94/4885CYP2D6 3951/4885DRD2 1917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.