Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 8/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | KDM5C | P41229 | 4/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.50 |
| ▸ | KDM4A | O75164 | 4/20 | 0.50 |
| ▸ | KDM6B | O15054 | 3/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.50 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PTGES | O14684 | 2/20 | 0.46 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | TET3 | O43151 | 1/20 | 0.45 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12420751 | 0.86 | KDM5A (0.57) | KDM5AKDM5BKDM4CALKBH1KDM2B | |
| SCHEMBL837794 | 0.84 | NR4A2 (0.58) | KDM5AKDM5BKDM4EKDM5CKDM4C | |
| SCHEMBL12420867 | 0.84 | NR4A2 (0.50) | KDM5AKDM5BKDM4CNR1H4NR4A2 | |
| SCHEMBL12420743 | 0.82 | KDM5A (0.55) | KDM5AKDM5BKDM4EKDM5CKDM4C | |
| SCHEMBL2195411 | 0.82 | KDM4C (0.55) | KDM5AKDM5BKDM4EKDM5CKDM4C | |
| SCHEMBL2546283 | 0.81 | KDM4C (0.50) | KDM5AKDM5BKDM4EKDM5CKDM4C | |
| SCHEMBL25049489 | 0.80 | KDM4C (0.57) | KDM5AKDM5BKDM4EKDM5CKDM4C | |
| SCHEMBL12420863 | 0.79 | NR3C2 (0.46) | KDM5AKDM5BKDM4EKDM5CKDM4C | |
| SCHEMBL12800159 | 0.79 | KDM4C (0.45) | KDM5AKDM5BKDM4EKDM5CKDM4C | |
| SCHEMBL14967550 | 0.79 | POLB (0.55) | KDM4EKDM5CKDM4CKDM4AKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | FAAH, FAAH2, UTS2R | KDM5A 301/4885KDM5B 304/4885KDM4E 1146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.