Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 6/20 | 0.57 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.57 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12420736 | 0.86 | KDM5A (0.52) | KDM5AKDM5BKDM4CNR4A2LOXL2 | |
| SCHEMBL958328 | 0.80 | GPR52 (0.57) | KDM5AKDM5BKDM4CNR4A2CYP4F2 | |
| SCHEMBL12420743 | 0.78 | KDM5A (0.55) | KDM5AKDM5BKDM4CNR3C2CYP4F2 | |
| SCHEMBL2196514 | 0.76 | KDM5A (0.77) | KDM5AKDM5BKDM4CNR4A2NR3C2 | |
| SCHEMBL837794 | 0.75 | NR4A2 (0.58) | KDM5AKDM5BKDM4CNR4A2MRGPRX4 | |
| SCHEMBL12420867 | 0.74 | NR4A2 (0.50) | KDM5AKDM5BKDM4CNR4A2MRGPRX4 | |
| SCHEMBL2546283 | 0.74 | KDM4C (0.50) | KDM5AKDM5BKDM4CLOXL2 | |
| SCHEMBL25049489 | 0.73 | KDM4C (0.57) | KDM5AKDM5BKDM4C | |
| SCHEMBL2195411 | 0.73 | KDM4C (0.55) | KDM5AKDM5BKDM4CNR4A2ALKBH1 | |
| SCHEMBL12420863 | 0.72 | NR3C2 (0.46) | KDM5AKDM5BKDM4CNR3C2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | FAAH, FAAH2, UTS2R | KDM5A 301/4885KDM5B 304/4885KDM4C 448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.