Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 5/20 | 0.55 |
| ▸ | KDM5B | Q9UGL1 | 5/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.51 |
| ▸ | KDM4A | O75164 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KDM6B | O15054 | 2/20 | 0.44 |
| ▸ | KDM5C | P41229 | 2/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.44 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12420849 | 0.86 | KDM5A (0.62) | KDM5AKDM5BKDM4CKDM4AKDM4E | |
| SCHEMBL2195411 | 0.84 | KDM4C (0.55) | KDM5AKDM5BKDM4CKDM4AKDM4E | |
| SCHEMBL12420863 | 0.84 | NR3C2 (0.46) | KDM5AKDM5BKDM4CKDM4AKDM4E | |
| SCHEMBL12420736 | 0.82 | KDM5A (0.52) | KDM5AKDM5BKDM4CKDM4AKDM4E | |
| SCHEMBL12420861 | 0.79 | KDM5A (0.51) | KDM5AKDM5BKDM4CKDM4AKDM4E | |
| SCHEMBL12420751 | 0.78 | KDM5A (0.57) | KDM5AKDM5BKDM4CNR3C2MRGPRX4 | |
| SCHEMBL16453501 | 0.78 | TAAR1 (0.40) | KDM4ENR3C2MAOBSIRT2MAPT | |
| SCHEMBL31729821 | 0.76 | TP53 (0.55) | KDM5AKDM5BKDM4CRARB | |
| SCHEMBL16453515 | 0.76 | NR3C2 (0.41) | KDM4ENR3C2MAOB | |
| SCHEMBL2546283 | 0.75 | KDM4C (0.50) | KDM5AKDM5BKDM4CKDM4AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | FAAH, FAAH2, UTS2R | KDM5A 301/4885KDM5B 304/4885KDM4C 448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.