SCHEMBL124208

SCHEMBL124208

[C]1CCc2ccccc2O1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.39
MAOB P27338 2/20 0.39
TSHR P16473 1/20 0.35
ABCG2 Q9UNQ0 1/20 0.33
ITGB2 P05107 1/20 0.33
ICAM1 P05362 1/20 0.33
ITGAL P20701 1/20 0.33
OXTR P30559 1/20 0.33
GAA P10253 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HTR2C P28335 1/20 0.31
SIGMAR1 Q99720 1/20 0.30
LMNA P02545 2/20 0.30
CRHBP P24387 2/20 0.30
CRHR2 Q13324 2/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL884061 0.89 TSHR (0.44) MAOAMAOBTSHRABCG2ITGB2
SCHEMBL141166 0.78 MAOA (0.37) MAOAMAOBTSHRABCG2ITGB2
SCHEMBL3128 0.76
SCHEMBL2851479 0.76
SCHEMBL8309834 0.71 MAOB (0.40) MAOAMAOBTSHR
SCHEMBL261547 0.70 MAOA (0.37) MAOAMAOBABCG2ITGB2ICAM1
SCHEMBL9116473 0.68 MAOA (0.35) MAOAMAOBTSHRABCG2ITGB2
SCHEMBL291589 0.68 GAA (0.36) MAOAMAOBTSHRABCG2ITGB2
SCHEMBL519471 0.68 OXTR (0.52) MAOAMAOBABCG2ITGB2ICAM1
SCHEMBL133442 0.68 ITGB2 (0.56) MAOAMAOBTSHRABCG2ITGB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3348 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118317956-A Bis (hetero) aryl thioether oxadiazines as fungicidal compounds 拜耳公司 2024-07-09 CN claimed
WO-2023091554-A9 NOVEL HETEROARYL-UREA COMPOUNDS AS KV7.2 INHIBITORS ICAGEN, LLC (US) 2024-05-23 WO claimed
US-20230354808-A1 METHOD OF CONTROLLING SOYBEAN RUST FUNGUS RESISTANT TO QOI FUNGICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-11-09 US claimed
WO-2023091554-A1 NOVEL HETEROARYL-UREA COMPOUNDS AS KV7.2 INHIBITORS ICAGEN, LLC (US) 2023-05-25 WO claimed
CN-109923116-B [1,2,4] triazolo [1,5-a ] pyrimidine derivatives as PDE2 inhibitors 詹森药业有限公司 2022-12-06 CN claimed
US-11225470-B2 Tetrazolinone compounds and its use as pest control agents SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-01-18 US claimed
CN-113861103-A Method for synthesizing pyridine, bipyridine and terpyridine ligands 南方科技大学 2021-12-31 CN claimed
US-20210369680-A1 METHODS OF TREATING DISEASES AND DISORDERS RESULTING FROM BETA CORONAVIRUS INFECTION T3D THERAPEUTICS INC (US) 2021-12-02 US claimed
WO-2021161218-A1 SULFINIC ACID AND SULFONIC ACID COMPOUNDS FOR USE IN MODULATING PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS INORBIT THERAPEUTICS AB (SE) 2021-08-19 WO claimed
WO-2021153794-A1 METHOD OF CONTROLLING SOYBEAN RUST FUNGUS RESISTANT TO QOI FUNGICIDE 住友化学株式会社 2021-08-05 WO claimed
US-5338743-A Pancreatitis FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-08-16 US claimed
WO-1994002489-A1 CEPHALOSPORINS AND 1-CARBA-1-DETHIA CEPHALOSPORINS SMITHKLINE BEECHAM PLC (GB) 1994-02-03 WO claimed
US-5260316-A Lipoxygenase inhibitor CIBA-GEIGY CORPORATION (US) 1993-11-09 US claimed
EP-0560163-A1 Imidazolylmethyl substituted phenylacetic-acid amides, process for their preparation and their pharmaceutical application BAYER AG (DE) 1993-09-15 EP claimed
EP-0560162-A1 Imidazolylmethyl substituted phenylacetic-acid amides, process for their preparation and their pharmaceutical application BAYER AG (DE) 1993-09-15 EP claimed
US-5204346-A Cognition activators; analgesics; antidepressants; vasodilation; cardiovascular and urogential disorders; FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-04-20 US claimed
EP-0467248-A2 Pyrazolopyridine compound and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-01-22 EP claimed
US-4810609-A ELECTROGRAPHY MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1989-03-07 US claimed
US-4808505-A Photosensitive member with enamine charge transport material MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1989-02-28 US claimed
US-4560447-A Electrolytic process for preparation of α-alkylated acetic acid derivatives OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1985-12-24 US claimed