⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3128 | 1.00 | — | — | |
| SCHEMBL450202 | 0.76 | MAOA (0.39) | — | |
| SCHEMBL5065 | 0.76 | MAOA (0.39) | — | |
| SCHEMBL124208 | 0.76 | MAOA (0.39) | — | |
| SCHEMBL453819 | 0.76 | MAOA (0.39) | — | |
| SCHEMBL61449 | 0.75 | MAOA (0.54) | — | |
| SCHEMBL884061 | 0.75 | TSHR (0.44) | — | |
| SCHEMBL7546456 | 0.73 | KDM4E (0.39) | — | |
| SCHEMBL261547 | 0.73 | MAOA (0.37) | — | |
| SCHEMBL519471 | 0.72 | OXTR (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152670-B1 | BRIDGED SIX-MEMBERED RING COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-12-25 | — | — | EP | claimed |
| US-20100130545-A1 | BRIDGED SIX-MEMBERED RING COMPOUNDS | IDORSIA PHARMACEUTICALS LTD (CH) | 2010-05-27 | — | — | US | claimed |
| EP-2152670-A1 | BRIDGED SIX-MEMBERED RING COMPOUNDS | Actelion Pharmaceuticals Ltd. (CH) | 2010-02-17 | — | — | EP | claimed |
| WO-2008132679-A1 | BRIDGED SIX-MEMBERED RING COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2008-11-06 | — | — | WO | claimed |
| US-6946207-B2 | Electroconductive device, organic electroluminescence device using the device and process for producing the electroconductive device | CANON KABUSHIKI KAISHA (JP) | 2005-09-20 | — | — | US | claimed |
| US-20020135292-A1 | Electroconductive device, organic electroluminescence device using the device and process for producing the electroconductive device | CANON KABUSHIKI KAISHA (JP) | 2002-09-26 | — | — | US | claimed |
| EP-2152670-B1 | BRIDGED SIX-MEMBERED RING COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-12-25 | — | — | EP | disclosed |
| US-8202885-B2 | Bridged six-membered ring compounds | ACTELION PHARMACEUTICALS LTD. (CH) | 2012-06-19 | — | — | US | disclosed |
| US-20100130545-A1 | BRIDGED SIX-MEMBERED RING COMPOUNDS | IDORSIA PHARMACEUTICALS LTD (CH) | 2010-05-27 | — | — | US | disclosed |
| EP-2152670-A1 | BRIDGED SIX-MEMBERED RING COMPOUNDS | Actelion Pharmaceuticals Ltd. (CH) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008132679-A1 | BRIDGED SIX-MEMBERED RING COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2008-11-06 | — | — | WO | disclosed |
| US-20070042295-A1 | Optical data carrier comprising a polymeric network in the information layer | LANXESS DEUTSCHLAND GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
| EP-1611574-A1 | OPTICAL DATA CARRIER COMPRISING A POLYMERIC NETWORK IN THE INFORMATION LAYER | LANXESS Deutschland GmbH (DE) | 2006-01-04 | — | — | EP | disclosed |
| US-6946207-B2 | Electroconductive device, organic electroluminescence device using the device and process for producing the electroconductive device | CANON KABUSHIKI KAISHA (JP) | 2005-09-20 | — | — | US | disclosed |
| WO-2004086390-A1 | OPTICAL DATA CARRIER COMPRISING A POLYMERIC NETWORK IN THE INFORMATION LAYER | LANXESS DEUTSCHLAND GMBH (DE) | 2004-10-07 | — | — | WO | disclosed |
| EP-1377978-A2 | OPTICAL DATA CARRIER WHOSE INFORMATION LAYER CONTAINS A LIGHT-ABSORBING COMPOUND HAVING A NUMBER OF CHROMOPHORIC CENTERS | Bayer Chemicals AG (DE) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002086878-A2 | OPTICAL DATA CARRIER WHOSE INFORMATION LAYER CONTAINS A LIGHT-ABSORBING COMPOUND HAVING A NUMBER OF CHROMOPHORIC CENTERS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-31 | — | — | WO | disclosed |
| US-20020155381-A1 | Optical data carrier comprising a light-absorbent compound having a plurality of chromophoric centres in the information layer | LANXESS DEUTSCHLAND GMBH (DE) | 2002-10-24 | — | — | US | disclosed |
| US-20020135292-A1 | Electroconductive device, organic electroluminescence device using the device and process for producing the electroconductive device | CANON KABUSHIKI KAISHA (JP) | 2002-09-26 | — | — | US | disclosed |