SCHEMBL12422804

SCHEMBL12422804

C/C(=C\N(Cc1ccc(C)cc1)Cc1ccc(C)cc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.43
TAS2R14 Q9NYV8 1/20 0.40
G6PC1 P35575 1/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
TSPO P30536 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
MEP1B Q16820 1/20 0.37
CNR2 P34972 1/20 0.37
POLB P06746 2/20 0.37
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MCHR1 Q99705 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12422799 0.90 G6PC1 (0.49) G6PC1NPC1RAB9ATSPOMEN1
SCHEMBL12422802 0.85 CYP2C19 (0.44) CYP2C19TAS2R14G6PC1NPC1RAB9A
SCHEMBL12422835 0.78 CYP2C19 (0.49) CYP2C19TAS2R14NPC1RAB9AMEN1
SCHEMBL136255 0.74 ALDH1A1 (0.39) MEN1KMT2ACES2CES1SMN1; SMN2
SCHEMBL19803812 0.74 ALDH1A1 (0.39) MEN1KMT2ACES2CES1SMN1; SMN2
SCHEMBL6548125 0.74 MEN1 (0.43) NPC1RAB9AMEN1KMT2ACES2
SCHEMBL1403755 0.72 ALDH1A1 (0.48) G6PC1NPC1RAB9ATSPOLMNA
Hydrochloric Acid SCHEMBL5671834 0.71 ALDH1A1 (0.46) G6PC1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL12422791 0.71 G6PC1 (0.43) G6PC1MEN1KMT2A
SCHEMBL29190232 0.70 HDAC1 (0.61) NPC1RAB9AMEN1KMT2ACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977020-B2 Electrophotographic photoreceptor containing enamine compound, image formation apparatus provided with the same, enamine compound and method for producing the same SHARP KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-7977020-B2 Electrophotographic photoreceptor containing enamine compound, image formation apparatus provided with the same, enamine compound and method for producing the same SHARP KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-20080286671-A1 Electrophotographic photoreceptor containing enamine compound, image formation apparatus provided with the same, enamine compound and method for producing the same SHARP KABUSHIKI KAISHA (JP) 2008-11-20 US disclosed
US-20080286671-A1 Electrophotographic photoreceptor containing enamine compound, image formation apparatus provided with the same, enamine compound and method for producing the same SHARP KABUSHIKI KAISHA (JP) 2008-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080286671-A1 Electrophotographic photoreceptor containing enamine compound, image formation apparatus provided with the same, enamine compound and method for producing the same SLC1A2, SLC1A1, SLC18A1 CYP2C19 2058/4885TAS2R14 2159/4885G6PC1 4450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.