SCHEMBL12422833

SCHEMBL12422833

C(=C(c1ccccc1)c1ccccc1)N(CC1CCCO1)CC1CCCO1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.49
OXTR P30559 7/20 0.47
ALDH1A1 P00352 3/20 0.46
GLA P06280 1/20 0.46
ALOX12 P18054 1/20 0.46
AVPR1A P37288 6/20 0.41
AVPR2 P30518 1/20 0.41
AVPR1B P47901 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
RAB9A P51151 1/20 0.41
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12422828 0.75 HDAC1 (0.42) SMN1; SMN2
SCHEMBL22187008 0.70 HPGD (0.69) HPGDALDH1A1GLAALOX12SMN1; SMN2
SCHEMBL28476929 0.69 OXTR (0.50) HPGDOXTRALDH1A1AVPR1ASMN1; SMN2
SCHEMBL28473802 0.69 OXTR (0.50) HPGDOXTRALDH1A1AVPR1ASMN1; SMN2
SCHEMBL28473805 0.69 OXTR (0.50) HPGDOXTRALDH1A1AVPR1ASMN1; SMN2
SCHEMBL18357628 0.69 HPGD (0.61) HPGDOXTRALDH1A1GLAALOX12
SCHEMBL22187009 0.68 HPGD (0.49) HPGDOXTRALDH1A1GLAALOX12
SCHEMBL18088562 0.68 OXTR (0.44) HPGDOXTRALDH1A1AVPR1AAVPR2
SCHEMBL22074352 0.67 ALDH1A1 (0.48) HPGDOXTRALDH1A1AVPR1AAVPR2
SCHEMBL10473220 0.67 ALDH1A1 (0.49) HPGDOXTRALDH1A1AVPR1AAVPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977020-B2 Electrophotographic photoreceptor containing enamine compound, image formation apparatus provided with the same, enamine compound and method for producing the same SHARP KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-7977020-B2 Electrophotographic photoreceptor containing enamine compound, image formation apparatus provided with the same, enamine compound and method for producing the same SHARP KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-20080286671-A1 Electrophotographic photoreceptor containing enamine compound, image formation apparatus provided with the same, enamine compound and method for producing the same SHARP KABUSHIKI KAISHA (JP) 2008-11-20 US disclosed
US-20080286671-A1 Electrophotographic photoreceptor containing enamine compound, image formation apparatus provided with the same, enamine compound and method for producing the same SHARP KABUSHIKI KAISHA (JP) 2008-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080286671-A1 Electrophotographic photoreceptor containing enamine compound, image formation apparatus provided with the same, enamine compound and method for producing the same SLC1A2, SLC1A1, SLC18A1 HPGD 596/4885OXTR 3688/4885ALDH1A1 869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.