Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | OXTR | P30559 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20777353 | 0.84 | TRPM8 (0.53) | ALDH1A1OXTRHPGDL3MBTL1 | |
| SCHEMBL10745005 | 0.82 | ALDH1A1 (0.55) | ALDH1A1OXTRHPGDLMNATSHR | |
| SCHEMBL22187009 | 0.82 | HPGD (0.49) | ALDH1A1OXTRHPGDLMNATSHR | |
| SCHEMBL20772987 | 0.79 | TRPM8 (0.52) | ALDH1A1HPGDLMNATSHRALOX15 | |
| SCHEMBL29779959 | 0.79 | TRPM8 (0.52) | ALDH1A1HPGDLMNATSHRALOX15 | |
| SCHEMBL29779991 | 0.77 | TRPM8 (0.61) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL20772759 | 0.77 | TRPM8 (0.61) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL611099 | 0.75 | OXTR (0.43) | ALDH1A1OXTRHPGDLMNAAVPR1A | |
| SCHEMBL22074368 | 0.75 | TRPM8 (0.51) | ALDH1A1HPGDLMNAKMT2AMAPT | |
| SCHEMBL20773077 | 0.75 | HPGD (0.66) | ALDH1A1HPGDKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3675809-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2020-07-08 | — | — | EP | claimed |
| EP-3675809-B1 | USE OF PHYSIOLOGICAL COOLING INGREDIENTS AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2023-09-27 | — | — | EP | disclosed |
| CN-111343963-B | Use of physiologically cooling active ingredients and compositions comprising such active ingredients | 巴斯夫欧洲公司 | 2023-09-12 | — | — | CN | disclosed |
| US-11434220-B2 | Use of physiological cooling active ingredients, and compositions comprising such active ingredients | BASF SE (DE) | 2022-09-06 | — | — | US | disclosed |
| EP-3675809-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2020-07-08 | — | — | EP | disclosed |
| US-20200190052-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11434220-B2 | Use of physiological cooling active ingredients, and compositions comprising such active ingredients | TRPM8, TRPM7, TRPM5 | ALDH1A1 1810/4885OXTR 1072/4885HPGD 1710/4885 |
| US-20200190052-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS | TRPM8, TRPM7, TRPM5 | ALDH1A1 1810/4885OXTR 1072/4885HPGD 1710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.