SCHEMBL12422834

SCHEMBL12422834

CC(C)C/C(=C\N(Cc1ccccc1)Cc1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PC1 P35575 1/20 0.39
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
TSHR P16473 3/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
SLC6A2 P23975 1/20 0.38
HTR2A P28223 1/20 0.38
SLC6A4 P31645 1/20 0.38
ADRA1A P35348 1/20 0.38
OPRK1 P41145 1/20 0.38
SLC6A3 Q01959 1/20 0.38
KCNH2 Q12809 1/20 0.38
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.36
AOC3 Q16853 1/20 0.35
ALOX5 P09917 1/20 0.35
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
USP2 O75604 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12422885 0.81 G6PC1 (0.42) G6PC1MEN1KMT2ATSHRALDH1A1
SCHEMBL4827392 0.75 HDAC1 (0.38) TSHRADRA2BHTR2AKCNH2ALDH1A1
SCHEMBL12422799 0.74 G6PC1 (0.49) G6PC1MEN1KMT2ATSHRALDH1A1
SCHEMBL28312134 0.73 SMN1; SMN2 (0.41) ALDH1A1HPGDLMNAMAOAMAOB
SCHEMBL12422791 0.73 G6PC1 (0.43) G6PC1MEN1KMT2ATSHRALDH1A1
SCHEMBL1403755 0.71 ALDH1A1 (0.48) G6PC1TSHRALDH1A1AOC3NPC1
SCHEMBL6072978 0.70 ASF1A (0.37) KMT2AALDH1A1HPGDLMNAMAOA
SCHEMBL12422840 0.70 KMT2A (0.38) G6PC1MEN1KMT2ATSHRADRA2B
Hydrochloric Acid SCHEMBL5671834 0.70 ALDH1A1 (0.46) G6PC1TSHRALDH1A1AOC3NPC1
SCHEMBL12422836 0.67 CYP2C19 (0.42) G6PC1MEN1KMT2ATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977020-B2 Electrophotographic photoreceptor containing enamine compound, image formation apparatus provided with the same, enamine compound and method for producing the same SHARP KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-7977020-B2 Electrophotographic photoreceptor containing enamine compound, image formation apparatus provided with the same, enamine compound and method for producing the same SHARP KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-20080286671-A1 Electrophotographic photoreceptor containing enamine compound, image formation apparatus provided with the same, enamine compound and method for producing the same SHARP KABUSHIKI KAISHA (JP) 2008-11-20 US disclosed
US-20080286671-A1 Electrophotographic photoreceptor containing enamine compound, image formation apparatus provided with the same, enamine compound and method for producing the same SHARP KABUSHIKI KAISHA (JP) 2008-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080286671-A1 Electrophotographic photoreceptor containing enamine compound, image formation apparatus provided with the same, enamine compound and method for producing the same SLC1A2, SLC1A1, SLC18A1 G6PC1 4450/4885MEN1 1117/4885KMT2A 1002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.